SCHEMBL27460680

SCHEMBL27460680

c1ccc(Cn2cc(N3CCC(C4OCCO4)CC3)cn2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ SCD O00767 8/20 0.42
▸ SCD5 Q86SK9 6/20 0.42
▸ LMNA P02545 2/20 0.39
▸ PKM P14618 2/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ TAS2R8 Q9NYW2 5/20 0.39
▸ RIPK1 Q13546 1/20 0.38
▸ ADORA3 P0DMS8 1/20 0.37
▸ ADORA2A P29274 1/20 0.37
▸ ADORA2B P29275 1/20 0.37
▸ ADORA1 P30542 1/20 0.37
▸ MAPT P10636 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27460671 0.81 — —
SCHEMBL14336874 0.75 LMNA (0.52) L3MBTL1LMNASMN1; SMN2MAPT
SCHEMBL22957172 0.75 SIGMAR1 (0.50) L3MBTL1LMNAPKMNPSR1USP2
SCHEMBL27830169 0.74 ACHE (0.57) —
SCHEMBL5544837 0.67 ME3 (0.46) L3MBTL1LMNAPKMMAPT
SCHEMBL25170721 0.67 MCHR1 (0.45) LMNASMN1; SMN2MAPTHTT
Trifluoroacetic Acid SCHEMBL30282920 0.67 LMNA (0.45) L3MBTL1SCDSCD5LMNAPKM
SCHEMBL17010774 0.66 DRD4 (0.42) L3MBTL1LMNAPKMNPSR1USP2
SCHEMBL23459580 0.66 NR1H4 (0.40) L3MBTL1USP2SMN1; SMN2MAPTHTT
SCHEMBL7247446 0.65 L3MBTL1 (0.51) L3MBTL1SCDSCD5LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539849-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 Therapeutics, Inc. (US) 2025-04-23 — — EP disclosed
WO-2023244764-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 THERAPEUTICS, INC. (US) 2023-12-21 — — WO disclosed
WO-2023244764-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 THERAPEUTICS, INC. (US) 2023-12-21 — — WO disclosed
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