Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747010 | 0.92 | ALDH1A1 (0.56) | NPC1TSHRALDH1A1ALOX15TDP1 | |
| SCHEMBL2127765 | 0.90 | TSHR (0.55) | NPC1TSHRALDH1A1ALOX15LMNA | |
| SCHEMBL27888119 | 0.88 | NPC1 (0.46) | NPC1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28310474 | 0.87 | LMNA (0.57) | NPC1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4528196 | 0.87 | HSD17B10 (0.58) | NPC1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL16920457 | 0.84 | NPC1 (0.54) | NPC1TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL28762966 | 0.82 | BCAT2 (0.52) | TSHRALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL15537502 | 0.82 | NPC1 (0.41) | NPC1TSHRALDH1A1ALOX15TDP1 | |
| SCHEMBL2747742 | 0.82 | ACMSD (0.46) | NPC1ALDH1A1ALOX15HSD17B10HPGD | |
| SCHEMBL9067707 | 0.81 | NPC1 (0.40) | NPC1TSHRALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868820-B2 | Polyarylene materials | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-01-16 | — | — | US | claimed |
| CN-105384915-A | Polyarylene materials | ROHM & HAAS ELECT MATERIALS KOREA LTD | 2016-03-09 | — | — | CN | claimed |
| US-20160060393-A1 | POLYARYLENE MATERIALS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2016-03-03 | — | — | US | claimed |
| EP-2990430-A1 | POLYARYLENE MATERIALS | Rohm and Haas Electronic Materials LLC (US) | 2016-03-02 | — | — | EP | claimed |
| WO-2012005648-A1 | UNSATURATED OLIGIO OR POLYESTER | PERSTORP AB (SE) | 2012-01-12 | — | — | WO | claimed |
| US-5066771-A | Endcapped with triple bonds, made from aromatic acid and amine, self-curing, polyimide properties, soluble in organic solvents | KOZO IIZUKA, DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1991-11-19 | — | — | US | claimed |
| US-12379660-B2 | Adhesion promoting photoresist underlayer composition | DUPONT ELECTRONIC MATERIALS INTERNATIONAL, LLC (US) | 2025-08-05 | — | — | US | disclosed |
| US-20220197143-A1 | ADHESION PROMOTING PHOTORESIST UNDERLAYER COMPOSITION | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2022-06-23 | — | — | US | disclosed |
| US-11175581-B2 | Aromatic resins for underlayers | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2021-11-16 | — | — | US | disclosed |
| US-10894848-B2 | Polyarylene resins | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2021-01-19 | — | — | US | disclosed |
| US-10790146-B2 | Aromatic resins for underlayers | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2020-09-29 | — | — | US | disclosed |
| US-20180171069-A1 | POLYARYLENE RESINS | ROHM & HAAS ELECT MAT (US) | 2018-06-21 | — | — | US | disclosed |
| EP-3336125-A1 | POLYARYLENE RESIN COMPOSITIONS | Rohm and Haas Electronic Materials LLC (US) | 2018-06-20 | — | — | EP | disclosed |
| US-5689004-A | CONTROLLED MOLECULAR WEIGHT IMIDE OLIGOMERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1997-11-18 | — | — | US | disclosed |
| US-5681967-A | ENDCAPPING POLYAMIC ACIDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1997-10-28 | — | — | US | disclosed |
| US-5606014-A | MOLECULAR WEIGHT CONTROL; CYCLODEHYDRATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1997-02-25 | — | — | US | disclosed |
| WO-1997006200-A1 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NATIONAL AERONAUTICS & SPACE ADMINISTRATION (US) | 1997-02-20 | — | — | WO | disclosed |
| US-5567800-A | MOLECULAR WEIGHT CONTROLLED AROMATIC POLYIMIDES; ELONGATION, HIGH GLASS TRANSITION TEMPERATURE, TOUGHNESS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1996-10-22 | — | — | US | disclosed |
| US-5066771-A | Endcapped with triple bonds, made from aromatic acid and amine, self-curing, polyimide properties, soluble in organic solvents | KOZO IIZUKA, DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1991-11-19 | — | — | US | disclosed |
| US-5066771-A | Endcapped with triple bonds, made from aromatic acid and amine, self-curing, polyimide properties, soluble in organic solvents | KOZO IIZUKA, DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1991-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894848-B2 | Polyarylene resins | PIN1, HSD17B12, PCBP1 | NPC1 1717/4885TSHR 4165/4885ALDH1A1 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.