Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL27861841 | 0.90 | — | — | |
| SCHEMBL27965316 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL6732428 | 0.90 | — | — | |
| SCHEMBL17873989 | 0.90 | — | — | |
| SCHEMBL30606802 | 0.90 | — | — | |
| SCHEMBL28782875 | 0.82 | — | — | |
| Benzene SCHEMBL29110078 | 0.82 | ALDH1A1 (0.30) | — | |
| Boric Acid SCHEMBL28474443 | 0.79 | LMNA (0.31) | — | |
| SCHEMBL31587944 | 0.79 | — | — | |
| Water SCHEMBL28188815 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325613-A | Method for applying thermally conductive composition to electronic component | 美国陶氏有机硅公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109312206-A | Method for adhering silicone-based material to substrate | 美国陶氏有机硅公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-103804912-B | Silicone rubber compound, silicon rubber moulding article and preparation method thereof | 信越化学工业株式会社 | 2018-09-04 | — | — | CN | disclosed |
| CN-105051113-B | Include the silicone composition containing aryl group of alkaline-earth metal | 美国陶氏有机硅公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-107847421-A | Solid water-in-silicone composition with water release effect | 莱雅公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107428113-A | For manufacturing method, polymer foam composite prepared therefrom and the product prepared therefrom of polymer foam composite | 罗杰斯公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107207546-A | Ligand component, correlated response product, reaction product, the hydrosilylation catalysts comprising the ligand component and the hydrosilylation curable compositions of activation, and for preparing their correlation technique | 美国道康宁公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-105189672-B | 2-aminoimidazole functionalized silicone compositions and methods of making the same | 道康宁公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-104015433-B | Heat conductivity is combined silicone rubber sheet | 信越化学工业株式会社 | 2017-08-25 | — | — | CN | disclosed |
| CN-106133053-A | Thermoplastic polymer composition with low frictional resistance | 道康宁公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-103917603-B | The method forming the gel of the heat stability with improvement | 道康宁公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105899616-A | Curable organopolysiloxane composition and release film for use with dielectric ceramic layer-forming material using the same | 道康宁东丽株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-105377811-A | Cyanostilbenes | ROLIC AG | 2016-03-02 | — | — | CN | disclosed |
| CN-104168879-A | Pigment dyeing composition based on a particular acrylic polymer and on silicone copolymer, and dyeing method | OREAL | 2014-11-26 | — | — | CN | disclosed |
| CN-1720896-A | Cosmetic composition comprising a defined polymeric silicone and a gelling agent | OREAL (FR) | 2006-01-18 | — | — | CN | disclosed |
| CN-1148404-C | Stabilization of silicone elastomer molds | ���ǻ�ѧ��˾ | 2004-05-05 | — | — | CN | disclosed |
| CN-1284098-A | Stabilization of silicone elastomer molds | RHODIA CHIMIE SA (FR) | 2001-02-14 | — | — | CN | disclosed |