Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 13/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382188 | 0.86 | PARP1 (0.56) | MTNR1BMTNR1APARP1HSD17B2L3MBTL1 | |
| SCHEMBL27587725 | 0.83 | ESR1 (0.50) | MTNR1BMTNR1APARP1PTGIRPTGDR | |
| SCHEMBL27493421 | 0.82 | RAB9A (0.40) | PARP1PTGIRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27478927 | 0.80 | NPSR1 (0.45) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL27494617 | 0.80 | HTR3E (0.41) | PARP1PTGIRPTGDRNPC1RAB9A | |
| SCHEMBL27493797 | 0.75 | PTGIR (0.41) | MTNR1BMTNR1APTGIRNPC1RAB9A | |
| SCHEMBL28844152 | 0.74 | TRPM8 (0.56) | MTNR1BMTNR1APARP1PTGIRPTGDR | |
| SCHEMBL15779182 | 0.73 | MTNR1A (0.46) | MTNR1BMTNR1APARP1PTGIRPTGDR | |
| SCHEMBL27587717 | 0.73 | MTNR1A (0.46) | MTNR1BMTNR1APARP1PTGIRPTGDR | |
| SCHEMBL3470955 | 0.73 | CA1 (0.55) | PARP1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177343-A | Cell adhesion inhibitors | BIOGEN INC (US) | 1998-03-25 | — | — | CN | claimed |
| CN-1177343-A | Cell adhesion inhibitors | BIOGEN INC (US) | 1998-03-25 | — | — | CN | disclosed |