Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590584 | 0.77 | KDM4E (0.43) | MGLLAADATDPP4ALDH1A1L3MBTL1 | |
| SCHEMBL11803975 | 0.69 | MAPT (0.45) | DPP4NR1H2NR1H3ALDH1A1MAPT | |
| SCHEMBL30057301 | 0.68 | TACR1 (0.33) | AADATPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4964883 | 0.68 | SLC6A3 (0.40) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28856362 | 0.66 | GABRA1 (0.41) | FAAHDPP4NR1H2NR1H3GABRA1 | |
| SCHEMBL38660167 | 0.60 | ALDH1A1 (0.41) | FAAHMGLLAADATPSEN1PSEN2 | |
| SCHEMBL15314916 | 0.60 | GAA (0.46) | MGLLAADATPSEN1PSEN2APH1B | |
| SCHEMBL29707903 | 0.60 | MGLL (1.00) | FAAHMGLLALOX15DPP4NR1H2 | |
| SCHEMBL3482778 | 0.60 | MGLL (1.00) | FAAHMGLLALOX15DPP4NR1H2 | |
| SCHEMBL23721539 | 0.59 | ALOX15 (0.51) | FAAHMGLLALOX15ALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1224623-C | 1-phenylsulfonyl-1, 3-dihydro-2H-indol-2-one derivatives, their preparation and their therapeutic use | SANOFI ANWANTE (FR) | 2005-10-26 | — | — | CN | disclosed |
| CN-1533387-A | 1-phenysulfonyl-1,3-dihydro-2H-indole-2-one derivatives, their preparation and their therapeutic use | ����ɳŵ��-����������˾ | 2004-09-29 | — | — | CN | disclosed |