Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103275 | 0.86 | PRMT6 (0.37) | DDB1CRBNHRH3 | |
| SCHEMBL28103613 | 0.85 | MGLL (0.37) | DDB1CRBN | |
| SCHEMBL27380663 | 0.80 | ALOX5 (0.44) | — | |
| SCHEMBL27873898 | 0.80 | NOTUM (0.36) | — | |
| SCHEMBL28103270 | 0.80 | ALDH1A1 (0.34) | HRH3 | |
| SCHEMBL27671224 | 0.79 | ALOX5 (0.41) | — | |
| SCHEMBL28103278 | 0.78 | CALML3 (0.31) | — | |
| SCHEMBL28103276 | 0.77 | KDM4E (0.39) | HRH3 | |
| SCHEMBL28103547 | 0.76 | ADRB2 (0.41) | — | |
| SCHEMBL28103503 | 0.76 | NOTUM (0.40) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |
| CN-105061322-A | Preparation method of N-substituted 3-hydroxypyrazole compound | BEIJING NUTRICHEM CO LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-100345850-C | 3-phenyl-substituted pyridoindolones, their preparation and therapeutic use | SANOFI AVENTIS (FR) | 2007-10-31 | — | — | CN | disclosed |
| CN-1729190-A | 3-phenyl-substituted pyridoindolones, their preparation and therapeutic use | SANOFI AVENTIS (FR) | 2006-02-01 | — | — | CN | disclosed |
| CN-1240433-A | Process for preparing N-substituted 3-hydroxypyrazoles | BASF AG (DE) | 2000-01-05 | — | — | CN | disclosed |