Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27505117 | 0.85 | DDB1 (0.31) | DDB1CRBN | |
| SCHEMBL28103624 | 0.81 | LMNA (0.43) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL27873898 | 0.80 | NOTUM (0.36) | MGLLKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL27380663 | 0.80 | ALOX5 (0.44) | MEN1KMT2A | |
| SCHEMBL28103270 | 0.80 | ALDH1A1 (0.34) | MGLLALDH1A1LMNACYP2C19 | |
| SCHEMBL27671224 | 0.79 | ALOX5 (0.41) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL28103276 | 0.77 | KDM4E (0.39) | KDM4EPOLB | |
| SCHEMBL28103547 | 0.76 | ADRB2 (0.41) | SMN1; SMN2KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL28103503 | 0.76 | NOTUM (0.40) | HTR2AHTR2CTDP1 | |
| SCHEMBL28103632 | 0.76 | ALOX5 (0.46) | MGLLHTR2AHTR2CLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |