Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL27520693

O=S(=O)(Oc1ccccc1-c1ccc(F)cc1)C(F)(F)F.S

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.46
PTGS1 P23219 1/20 0.46
DRD1 P21728 6/20 0.40
HSD11B1 P28845 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
DRD2 P14416 4/20 0.39
DRD4 P21917 1/20 0.38
DRD5 P21918 1/20 0.38
DRD3 P35462 1/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
GLA P06280 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
STAT3 P40763 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL8733602 0.97 PTGS2 (0.46) PTGS2PTGS1DRD1HSD11B1SLC6A4
SCHEMBL367003 0.90 DRD2 (0.42) PTGS2DRD1DRD2DRD4DRD5
Hydrogen Sulfide SCHEMBL19066712 0.85 STAT3 (0.46) PTGS2MEN1ALDH1A1MAPTHPGD
Iodide SCHEMBL21220125 0.84 PTGS2 (0.39) PTGS2PTGS1DRD1SLC6A3DRD2
Iodide SCHEMBL8735153 0.84 PTGS2 (0.39) PTGS2PTGS1DRD1DRD2DRD4
Iodide SCHEMBL8737221 0.84 LMNA (0.43) PTGS2DRD1DRD2DRD4DRD5
Iodide SCHEMBL8735177 0.84 PTGS2 (0.44) PTGS2PTGS1DRD1SLC6A4SLC6A3
SCHEMBL7023211 0.84 DRD2 (0.42) DRD1HSD11B1DRD2DRD4DRD5
SCHEMBL28166225 0.83 PTGS2 (0.41) PTGS2PTGS1DRD1DRD2DRD4
SCHEMBL16926997 0.83 DRD2 (0.41) DRD1HSD11B1DRD2DRD4DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1243122-A Sulfonium salt and preparation method thereof KIM HO PETRO CHEMICAL CO LTD (KR) 2000-02-02 CN disclosed