SCHEMBL27539645

SCHEMBL27539645

Nc1cc(C(=O)[C]=O)cs1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4060825 0.76
SCHEMBL3107550 0.69 ALDH1A1 (0.46) CA2
SCHEMBL27347902 0.66 CA2 (0.37) DAOCA2
Hydrochloric Acid SCHEMBL6590194 0.65 PRSS1 (0.43)
SCHEMBL27393741 0.62 LMNA (0.41) DAOCA2
SCHEMBL10830583 0.61 CSNK2A1 (0.34)
SCHEMBL28873568 0.61
SCHEMBL22652964 0.58 SLC7A5 (0.52)
SCHEMBL144974 0.58 CES1 (0.52) DAOCA2
SCHEMBL1977231 0.56 TSHR (0.63) DAOCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1112927-A Enzymatic acylation of 3-hydroxymethyl cephalosporins BRISTOL MYERS SQUIBB CO (US) 1995-12-06 CN disclosed