Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23325684 | 0.82 | CTSS (0.41) | CTSSCTSKNOS1NOS3NOS2 | |
| SCHEMBL5195565 | 0.82 | CTSS (0.41) | CTSSCTSKNOS1NOS3NOS2 | |
| SCHEMBL10520251 | 0.82 | REN (0.41) | CTSSCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL26030844 | 0.80 | CTSS (0.42) | CTSSCTSKAAK1NR1H2KMT2A | |
| SCHEMBL7303335 | 0.79 | METAP2 (0.49) | CTSSCTSKRENMETAP2METAP1 | |
| SCHEMBL27709385 | 0.77 | CTSS (0.37) | CTSSCTSKAAK1SLC1A3SLC1A2 | |
| SCHEMBL29130862 | 0.77 | NOS1 (0.44) | CTSKNOS1NOS3NOS2 | |
| SCHEMBL28764792 | 0.76 | CTSK (0.43) | CTSSCTSKAAK1SLC1A3SLC1A2 | |
| SCHEMBL26805423 | 0.76 | CTSK (0.40) | CTSSCTSKAAK1SLC1A3SLC1A2 | |
| SCHEMBL26113626 | 0.76 | NOS1 (0.43) | CTSSCTSKNOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1303377-A | Amino piperidine derivatives as integrin alpha beta 3 antagonists | MEIJI SEIKA KAISHA (JP) | 2001-07-11 | — | — | CN | disclosed |