Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499554 | 0.85 | ALDH1A1 (0.40) | KDM4EMAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL5612906 | 0.84 | TTR (0.40) | CA1CA2CA9POLBKDM4E | |
| SCHEMBL27576157 | 0.79 | HNF4A (0.54) | MAPTL3MBTL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6816973 | 0.78 | KMO (0.39) | CA1CA2CA9CA12CA6 | |
| SCHEMBL27576101 | 0.78 | EGFR (0.41) | EGFRCA1CA2CA9KDM4E | |
| SCHEMBL27576158 | 0.76 | KDM4E (0.46) | EGFRCA1CA2CA9POLB | |
| SCHEMBL5594898 | 0.73 | PARP1 (0.39) | CA2POLBKDM4EGAAMAPT | |
| SCHEMBL27587710 | 0.73 | HSD17B1 (0.41) | DHODH | |
| SCHEMBL3663963 | 0.72 | POLB (0.59) | EGFRCA1CA2CA9POLB | |
| SCHEMBL26981142 | 0.72 | KDM4E (0.64) | EGFRCA1CA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1355697-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | CN | disclosed |