Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 5/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27587719 | 0.93 | HSD17B1 (0.36) | HSD17B1HSD17B2CYP3A4CYP2C9PTGES | |
| SCHEMBL27499553 | 0.78 | ACMSD (0.43) | AKR1C4AKR1C3AKR1C2AKR1C1CRHBP | |
| SCHEMBL6816973 | 0.77 | KMO (0.39) | CYP2C9AKR1C3 | |
| SCHEMBL6820924 | 0.74 | AKR1B1 (0.41) | — | |
| SCHEMBL27499554 | 0.73 | ALDH1A1 (0.40) | RAB9A | |
| SCHEMBL27576157 | 0.73 | HNF4A (0.54) | AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27558267 | 0.73 | EGFR (0.37) | DHODH | |
| SCHEMBL2089056 | 0.71 | NPSR1 (0.50) | RAB9A | |
| Bicarbonate SCHEMBL28112645 | 0.71 | HSD17B1 (0.73) | HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL27516293 | 0.70 | KDM4E (0.38) | CYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |