SCHEMBL275668

SCHEMBL275668

[BH4-].[BH4-].[BH4-].[BH4-].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5247960 1.00
SCHEMBL28767938 1.00 CA1 (0.33)
SCHEMBL28743251 1.00 CA1 (0.33)
SCHEMBL5398067 1.00
SCHEMBL80 1.00
SCHEMBL23200482 0.82
SCHEMBL6659176 0.82
SCHEMBL5649019 0.82
SCHEMBL9311111 0.82
SCHEMBL4308845 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194605-A1 BIOCIDAL HEAT AND MOISTURE EXCHANGE FILTER, METHOD FOR PREPARING A BIOCIDAL HEAT AND MOISTURE EXCHANGE FILTER, AND USE OF SILVER NANOPARTICLES MLA SUPRIMENTOS MEDICOS LTDA (BR) 2025-06-19 US claimed
EP-4338777-A1 BIOCIDAL HEAT AND MOISTURE EXCHANGE FILTER, METHOD FOR PREPARING A BIOCIDAL HEAT AND MOISTURE EXCHANGE FILTER, AND USE OF SILVER NANOPARTICLES MLA Suprimentos Medicos Ltda (BR) 2024-03-20 EP claimed
US-11791505-B2 Methods for purifying and recycling lead from spent lead-acid batteries CPS TECHNOLOGY HOLDINGS LLC (US) 2023-10-17 US claimed
EP-4176722-A1 ZERO-VALENT IRON, ESPECIALLY AGED FOR USE AS AN ANTIVIRAL AGENT, A METHOD FOR THE PREPARATION OF ZERO-VALENT IRON AND ZERO-VALENT IRON PREPARED USING THE METHOD Instytut Chemii Bioorganicznej Polskiej Akademii Nauk (PL) 2023-05-10 EP claimed
WO-2022236392-A1 BIOCIDAL HEAT AND MOISTURE EXCHANGE FILTER, METHOD FOR PREPARING A BIOCIDAL HEAT AND MOISTURE EXCHANGE FILTER, AND USE OF SILVER NANOPARTICLES MLA SUPRIMENTOS MEDICOS LTDA (BR) 2022-11-17 WO claimed
WO-2021122116-A1 PACKAGING MATERIAL HAVING ANTIMICROBIAL PROPERTIES, A METHOD FOR PRODUCING AND USE THEREOF UNIWERSYTET EKONOMICZNY W POZNANIU (PL) 2021-06-24 WO claimed
US-11015290-B2 Method for producing bleached wood fibre material BASF SE (DE) 2021-05-25 US claimed
US-10777858-B2 Methods for purifying and recycling lead from spent lead-acid batteries CPS TECHNOLOGY HOLDINGS LLC (US) 2020-09-15 US claimed
US-10428435-B2 Method for modifying an electrically conductive oxide surface, use for electrodeposition of copper on said surface COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2019-10-01 US claimed
EP-3232481-B1 PROCESS FOR MODIFIYING A SURFACE OF ELECTRICALLY CONDUCTIVE OXIDE, USE FOR THE ELECTRODEPOSITION OF COPPER THEREON COMMISSARIAT ENERGIE ATOMIQUE (FR) 2018-11-28 EP claimed
US-20130204032-A1 NEW PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF (3,4 DIMETHOXY-BICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL)NITRILE AND APPLICATION IN THE SYNTHESIS OF IVABRADINE LES LABORATOIRES SERVIER (FR) 2013-08-08 US claimed
US-8119794-B2 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid LES LABORATOIRES SERVIER (FR) 2012-02-21 US claimed
US-8101747-B2 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid LES LABORATOIRES SERVIER (FR) 2012-01-24 US claimed
EP-2241554-B1 Process for the synthesis of ivabradine and its pharmaceutically acceptable acid addition salts SERVIER LAB (FR) 2011-09-07 EP claimed
EP-2241553-B1 Process for the synthesis of ivabradine and its pharmaceutically acceptable acid addition salts SERVIER LAB (FR) 2011-07-20 EP claimed
EP-2166004-B1 New method for resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile and their application to the synthesis of ivabradine SERVIER LAB (FR) 2010-10-06 EP claimed
US-20100249398-A1 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid LES LABORATOIRES SERVIER (FR) 2010-09-30 US claimed
US-20100249397-A1 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid LES LABORATOIRES SERVIER (FR) 2010-09-30 US claimed
US-20100056778-A1 Process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl) nitrile and application in the synthesis of ivabradine LES LABORATOIRES SERVIER (FR) 2010-03-04 US claimed
EP-0572635-B1 COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME CENTRE NAT RECH SCIENT (FR) 1996-12-27 EP claimed