SCHEMBL1783525

SCHEMBL1783525

CNc1cc(NC)cc(NC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
HTR6 P50406 2/20 0.39
APP P05067 3/20 0.35
ALDH1A1 P00352 4/20 0.33
RECQL P46063 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
KIF11 P52732 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL31463955 0.96 TSHR (0.44) TSHRHTR6APPALDH1A1RECQL
SCHEMBL13198271 0.86 RAPGEF4 (0.42) TSHRHTR6ALDH1A1CYP3A4THRB
SCHEMBL12990555 0.83 HTR6 (0.47) TSHRHTR6ALDH1A1CA12CA1
SCHEMBL22852016 0.83 TSHR (0.36) TSHRHTR6ADRA2AADRA2BADRA2C
SCHEMBL3783747 0.83 TSHR (0.41) TSHRHTR6ALDH1A1MAPT
SCHEMBL5506973 0.83 RAPGEF4 (0.39) TSHRHTR6APPCA12CA1
SCHEMBL19709350 0.83 TSHR (0.36) TSHRHTR6ADRA2AADRA2BADRA2C
SCHEMBL20763402 0.78 TDP1 (0.46) TSHRHTR6ALDH1A1RECQLHSD17B10
SCHEMBL19844318 0.78 PTGS2 (0.36) TSHRHTR6ALDH1A1HSD17B10TP53
SCHEMBL20082558 0.78 GABRA1 (0.42) TSHRHTR6ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119816088-A Perovskite passivation material, passivation layer film, preparation method of perovskite passivation material and passivation layer film, and perovskite solar cell 中国华能集团清洁能源技术研究院有限公司 2025-04-11 CN disclosed
US-11078413-B2 Organic-inorganic hybrid perovskites, devices, and methods FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2021-08-03 US disclosed
US-20210032273-A1 Methods of Making Metal Halide Perovskites FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-02-04 US disclosed
WO-2020165600-A1 BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF BICYCLETX LIMITED (GB) 2020-08-20 WO disclosed
CN-108807939-A Preparation method of azo porous material/carbon nano tube composite electrode material 盐城师范学院 2018-11-13 CN disclosed
CN-108751163-A A kind of preparation method of nitrogen-doped porous carbon material 盐城师范学院 2018-11-06 CN disclosed
US-10059666-B2 Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions PLASTIPAK PACKAGING, INC. (US) 2018-08-28 US disclosed
EP-2499134-B1 OXYGEN SCAVENGERS, COMPOSITION COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS PLASTIPAK PACKAGING INC (US) 2018-04-18 EP disclosed
US-9896462-B1 Metal halide perovskites, methods, and devices FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2018-02-20 US disclosed
US-20180037813-A1 Organic-Inorganic Hybrid Perovskites, Devices, and Methods FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2018-02-08 US disclosed
US-8450398-B2 Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions CONSTAR INTERNATIONAL, INC. (US) 2013-05-28 US disclosed
EP-2499134-A2 OXYGEN SCAVENGERS, COMPOSITION COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS Constar International Inc. (US) 2012-09-19 EP disclosed
US-20120152822-A1 POLYMERIC MATRICES FORMED FROM MONOMERS COMPRISING A PROTECTED AMINE GROUP BL TECHNOLOGIES, INC. 2012-06-21 US disclosed
CN-102414215-A Structured organic films having an added functionality XEROX CORP 2012-04-11 CN disclosed
US-8034952-B2 Supramolecular assemblies and building blocks UNIVERSITY OF SOUTH FLORIDA (US) 2011-10-11 US disclosed
WO-2011060297-A2 OXYGEN SCAVENGERS, COMPOSITION COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS CONSTAR INTERNATIONAL, INC. (US) 2011-05-19 WO disclosed
US-20110117301-A1 OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2011-05-19 US disclosed
US-20100183598-A1 METHODS OF TREATING CARDIOVASCULAR DISORDERS CAROLUS THERAPEUTICS, INC. (US) 2010-07-22 US disclosed
US-20090143596-A1 Supramolecular Assemblies and Building Blocks UNIVERSITY OF SOUTH FLORIDA (US) 2009-06-04 US disclosed
CN-101384610-A 11 beta-hydroxyandrostan-4-en-3-ones SUN PHARMA ADVANCED RES CO LTD (IN) 2009-03-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037813-A1 Organic-Inorganic Hybrid Perovskites, Devices, and Methods TYR, HCN4, BMI1 TSHR 2345/4885HTR6 3091/4885APP 1945/4885
US-20210032273-A1 Methods of Making Metal Halide Perovskites SOD1, HCN4, KCND2 TSHR 3434/4885HTR6 2527/4885APP 2309/4885
US-11078413-B2 Organic-inorganic hybrid perovskites, devices, and methods TYR, HCN4, BMI1 TSHR 2345/4885HTR6 3091/4885APP 1945/4885
US-10059666-B2 Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions PRDX5, LPO, CAT TSHR 3903/4885HTR6 4332/4885APP 2080/4885
US-20110117301-A1 OXYGEN SCAVENGERS, COMPOSITIONS COMPRISING THE SCAVENGERS, AND ARTICLES MADE FROM THE COMPOSITIONS PRDX5, LPO, CAT TSHR 3903/4885HTR6 4332/4885APP 2080/4885
US-20090143596-A1 Supramolecular Assemblies and Building Blocks TERB1, TBCB, PARG TSHR 3936/4885HTR6 4319/4885APP 1058/4885
US-20100183598-A1 METHODS OF TREATING CARDIOVASCULAR DISORDERS TNNI3, TNNT2, FABP3 TSHR 4222/4885HTR6 56/4885APP 1350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.