Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | CACNB4 | O00305 | 5/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 5/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.47 |
| ▸ | CACNG3 | O60359 | 5/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.47 |
| ▸ | CACNB3 | P54284 | 5/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.47 |
| ▸ | CACNG7 | P62955 | 5/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 5/20 | 0.47 |
| ▸ | CACNG1 | Q06432 | 5/20 | 0.47 |
| ▸ | CACNB2 | Q08289 | 5/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.47 |
| ▸ | CACNA1E | Q15878 | 5/20 | 0.47 |
| ▸ | CACNA2D4 | Q7Z3S7 | 5/20 | 0.47 |
| ▸ | CACNA2D3 | Q8IZS8 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350921 | 0.99 | ACHE (0.50) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL3352639 | 0.90 | NR1H2 (0.53) | LMNAGLAALDH1A1TSHRADRB2 | |
| SCHEMBL3357664 | 0.87 | HRH3 (0.47) | LMNAGLAALDH1A1TSHRADRB2 | |
| SCHEMBL3355548 | 0.87 | HTR1D (0.48) | ACHEADRB2HTR1DGAA | |
| SCHEMBL3353653 | 0.87 | ACHE (0.50) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL3355352 | 0.86 | ADRB2 (0.47) | ACHEADRB2HTR1DGAA | |
| SCHEMBL3357851 | 0.82 | ICMT (0.54) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL3358868 | 0.78 | NR1H2 (0.53) | LMNAGLAALDH1A1TSHRNR1H2 | |
| SCHEMBL13537352 | 0.78 | CACNB4 (0.46) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL9400590 | 0.78 | ADRB2 (0.49) | LMNAALDH1A1ADRB2HTR1DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |