SCHEMBL2760653

SCHEMBL2760653

O=C(CBr)NCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12568580 0.88 RECQL (0.33) RECQL
SCHEMBL43231 0.84 HPGD (0.36)
SCHEMBL28333093 0.83 TERT (0.34) RECQL
SCHEMBL8735537 0.81 HPGD (0.37)
SCHEMBL4204236 0.81 PSMB8 (0.32)
SCHEMBL27324540 0.81 MGLL (0.30)
SCHEMBL9315493 0.81
SCHEMBL12386541 0.81 HPGD (0.36) RECQL
SCHEMBL22005285 0.81 GAA (0.33) RECQL
SCHEMBL22005196 0.81 RECQL (0.33) RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351830-B2 Conjugates for assays for oxycodone and oxymorphone SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2019-07-16 US disclosed
US-10351830-B2 Conjugates for assays for oxycodone and oxymorphone SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2019-07-16 US disclosed
US-20170362579-A1 CONJUGATES FOR ASSAYS FOR OXYCODONE AND OXYMORPHONE SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2017-12-21 US disclosed
US-20170362579-A1 CONJUGATES FOR ASSAYS FOR OXYCODONE AND OXYMORPHONE SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2017-12-21 US disclosed
EP-3234604-A2 CONJUGATES FOR ASSAYS FOR OXYCODONE AND OXYMORPHONE Siemens Healthcare Diagnostics Inc. (US) 2017-10-25 EP disclosed
WO-2016100113-A2 CONJUGATES FOR ASSAYS FOR OXYCODONE AND OXYMORPHONE SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2016-06-23 WO disclosed
US-9096653-B2 Multicomponent vaccine for malaria providing long-lasting immune responses against plasmodia THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2015-08-04 US disclosed
US-20150050314-A1 CONJUGATES OF PLASMODIUM FALCIPARUM SURFACE PROTEINS AS MALARIA VACCINES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE (US) 2015-02-19 US disclosed
US-8900599-B2 Conjugates of Plasmodium falciparum surface proteins as malaria vaccines THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2014-12-02 US disclosed
US-20130216570-A1 MULTICOMPONENT VACCINE FOR MALARIA PROVIDING LONG-LASTING IMMUNE RESPONSES AGAINST PLASMODIA The United States of America, as represented by he Secretary, Department of Health and Human 2013-08-22 US disclosed
US-20070218506-A1 Immunoassays for Buprenorphine and Norbuprenorphine DADE BEHRING INC. (US) 2007-09-20 US disclosed
US-20070218506-A1 Immunoassays for Buprenorphine and Norbuprenorphine DADE BEHRING INC. (US) 2007-09-20 US disclosed
US-7220842-B2 Immunoassays for buprenorphine and norbuprenorphine DADE BEHRING INC. (US) 2007-05-22 US disclosed
EP-1756570-A2 IMMUNOASSAYS FOR BUPRENORPHINE AND NORBUPRENORPHINE DADE BEHRING INC. (US) 2007-02-28 EP disclosed
WO-2005103697-A2 IMMUNOASSAYS FOR BUPRENORPHINE AND NORBUPRENORPHINE DADE BEHRING INC. (US) 2005-11-03 WO disclosed
US-20050221405-A1 Immunoassays for buprenorphine and norbuprenorphine SIEMENS HEALTHCARE DIAGNOSTICS INC. 2005-10-06 US disclosed
EP-0144154-B1 PROTEIN CONJUGATES OF PENICILLOIC ACID, THEIR PREPARATION AND USE SYNTEX (U.S.A.) INC. (US) 1989-07-12 EP disclosed
US-4816391-A LABELS, ANTIBIOTICS, POLYAMINES SYNTEX (U.S.A.) INC. (US) 1989-03-28 US disclosed
US-4596768-A Combining assay sample, enzyme-penicilloic acid conjugate and support containing antibodies, separating support, determining enzyme activity to indicate presence of penicilloic acid SYNTEX (U.S.A.) INC. (US) 1986-06-24 US disclosed
EP-0144154-A1 Protein conjugates of penicilloic acid, their preparation and use SYNTEX (U.S.A.) INC. (US) 1985-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150050314-A1 CONJUGATES OF PLASMODIUM FALCIPARUM SURFACE PROTEINS AS MALARIA VACCINES CD4, RPS25, OSBP2 RECQL 3665/4885
US-20130216570-A1 MULTICOMPONENT VACCINE FOR MALARIA PROVIDING LONG-LASTING IMMUNE RESPONSES AGAINST PLASMODIA CD47, NASP, CD69 RECQL 822/4885
US-20170362579-A1 CONJUGATES FOR ASSAYS FOR OXYCODONE AND OXYMORPHONE OPRK1, OPRM1, OPRL1 RECQL 1555/4885
US-20070218506-A1 Immunoassays for Buprenorphine and Norbuprenorphine HLA-B, HLA-C, SHBG RECQL 3457/4885
US-10351830-B2 Conjugates for assays for oxycodone and oxymorphone OPRK1, OPRM1, OPRL1 RECQL 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.