Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195206 | 0.80 | ALOX15 (0.62) | ALOX15LMNAMEN1KMT2AHPGDS | |
| SCHEMBL3859942 | 0.77 | ALOX15 (1.00) | ALOX15LMNAMEN1KMT2AHPGDS | |
| SCHEMBL33850 | 0.77 | WDR5 (0.68) | ALOX15LMNAMEN1KMT2AWDR5 | |
| SCHEMBL27804512 | 0.77 | WDR5 (0.68) | ALOX15LMNAMEN1KMT2AWDR5 | |
| Benzene SCHEMBL27549874 | 0.77 | WDR5 (0.68) | ALOX15LMNAMEN1KMT2AWDR5 | |
| SCHEMBL29376013 | 0.77 | WDR5 (0.68) | ALOX15LMNAMEN1KMT2AWDR5 | |
| SCHEMBL9148337 | 0.77 | LMNA (0.85) | ALOX15LMNAMEN1KMT2AHPGDS | |
| SCHEMBL29079300 | 0.76 | HPGDS (0.53) | ALOX15LMNAMEN1KMT2AHPGDS | |
| Hydrochloric Acid SCHEMBL608188 | 0.76 | LDHA (0.69) | ALOX15LMNAMEN1KMT2AWDR5 | |
| SCHEMBL4577224 | 0.76 | WDR5 (0.66) | ALOX15LMNAMEN1KMT2AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1549714-A | Aminoisoxazole derivatives active as kinase inhibitors | — | 2004-11-24 | — | — | CN | disclosed |