SCHEMBL27610936

SCHEMBL27610936

Oc1ccccc1-c1cnc(Cl)c(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.45
HSD17B10 Q99714 2/20 0.45
ALDH1A1 P00352 2/20 0.45
BCL2L1 Q07817 1/20 0.45
USP7 Q93009 1/20 0.44
EGLN1 Q9GZT9 2/20 0.44
EGLN3 Q9H6Z9 2/20 0.44
KMT2A Q03164 6/20 0.42
MEN1 O00255 5/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CHEK1 O14757 1/20 0.41
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALOX15 P16050 2/20 0.41
ALOX12 P18054 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
QPCT Q16769 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27586879 0.76 ALDH1A1 (0.50) HPGDHSD17B10ALDH1A1BCL2L1USP7
SCHEMBL27598925 0.76 HSD17B1 (0.40) HPGDHSD17B10ALDH1A1BCL2L1USP7
SCHEMBL15674853 0.74 ALDH1A1 (0.43) HPGDHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL7723870 0.73 AHR (0.54) HPGDHSD17B10ALDH1A1BCL2L1KMT2A
SCHEMBL7789344 0.73 ESR2 (0.64) HPGDHSD17B10ALDH1A1BCL2L1KMT2A
SCHEMBL27779502 0.73 HPGD (0.47) HPGDHSD17B10ALDH1A1BCL2L1KMT2A
SCHEMBL11245926 0.72 PTGS1 (0.46) ALDH1A1LMNANPSR1
SCHEMBL27610935 0.72 ESR2 (0.50) USP7KMT2AMEN1NPC1RAB9A
SCHEMBL31359594 0.71 HPGD (0.45) HPGDHSD17B10ALDH1A1BCL2L1KMT2A
SCHEMBL30498697 0.71 HPGD (0.45) HPGDHSD17B10ALDH1A1BCL2L1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100475790-C Pyridyloxyalkanoic acid amide derivatives as fungicides SYNGENTA LTD (GB) 2009-04-08 CN disclosed
CN-1599723-A Pyridyloxyalkanoic acid amide derivatives useful as fungicides SYNGENTA LTD (GB) 2005-03-23 CN disclosed