Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630016 | 0.83 | DRD2 (0.31) | — | |
| SCHEMBL27610601 | 0.79 | PPARG (0.41) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL27629478 | 0.79 | HDAC3 (0.33) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL27608930 | 0.78 | NPC1 (0.32) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL27629689 | 0.77 | MTNR1A (0.32) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL27590506 | 0.76 | NPC1 (0.32) | — | |
| SCHEMBL27590523 | 0.76 | BCHE (0.30) | — | |
| SCHEMBL27609196 | 0.76 | SIGMAR1 (0.47) | — | |
| SCHEMBL27608922 | 0.73 | NPC1 (0.33) | — | |
| SCHEMBL7766488 | 0.72 | HTT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |