Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811937 | 0.93 | LMNA (0.55) | LMNAGSK3BMEN1KMT2AMAPT | |
| SCHEMBL22677722 | 0.88 | GSK3B (0.51) | LMNAGSK3BMEN1KMT2AMAPT | |
| SCHEMBL15379288 | 0.86 | GSK3B (0.53) | LMNAGSK3BMEN1KMT2AMAPT | |
| SCHEMBL6650881 | 0.86 | MAPT (0.55) | LMNAGSK3BMAPTKDM4EALDH1A1 | |
| SCHEMBL5474416 | 0.85 | MEN1 (0.59) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28852443 | 0.84 | NPC1 (0.55) | LMNAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL11828535 | 0.82 | MAPT (0.52) | LMNAGSK3BMAPTKDM4EALDH1A1 | |
| SCHEMBL1110091 | 0.82 | KMT2A (0.62) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL27519955 | 0.81 | MAPT (0.63) | LMNAGSK3BMEN1KMT2AMAPT | |
| SCHEMBL11510574 | 0.81 | GSK3B (0.71) | LMNAGSK3BMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072476-B | Method for high-selectivity fluoromethylation of beta-keto ester compounds on oxygen | 南京理工大学 | 2022-10-21 | — | — | CN | claimed |
| CN-111072476-A | β -ketoester compound oxygen high-selectivity monofluoromethylation method | 南京理工大学 | 2020-04-28 | — | — | CN | claimed |
| CN-102718757-A | 2H-1-benzopyran-2-one compounds with alpha-glucosidase inhibitory activity and medicinal composition of 2H-1-benzopyran-2-one compounds | UNIV SHENYANG PHARMACEUTICAL | 2012-10-10 | — | — | CN | claimed |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | WASHINGTON UNIVERISTY (US) | 2025-09-23 | — | — | US | disclosed |
| EP-3745105-B1 | TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME | HITACHI LTD (JP) | 2025-08-27 | — | — | EP | disclosed |
| CN-112209907-B | Method for synthesizing dihydrofuran containing 1, 3-indenodione spiro framework by utilizing microchannel reaction device | 南京先进生物材料与过程装备研究院有限公司 | 2025-03-18 | — | — | CN | disclosed |
| US-12227524-B2 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2025-02-18 | — | — | US | disclosed |
| US-20240400247-A1 | TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD | HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) | 2024-12-05 | — | — | US | disclosed |
| EP-4431889-A1 | TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD | Hitachi Industrial Equipment Systems Co., Ltd. (JP) | 2024-09-18 | — | — | EP | disclosed |
| US-12085452-B2 | Temperature detection ink, temperature detection ink initialization method, temperature indicator, and article management system | HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) | 2024-09-10 | — | — | US | disclosed |
| CN-118619800-A | Amino dithioformate compound and preparation method thereof | 抚州三和医药化工有限公司 | 2024-09-10 | — | — | CN | disclosed |
| US-4637988-A | BINDING, ADSORPTION LANTHANIDE CHELATE COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0198356-A1 | Heat developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |
| US-4607041-A | CARDIOTONIC AGENTS | FISONS PLC (GB) | 1986-08-19 | — | — | US | disclosed |
| EP-0177033-A2 | Heat-developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0169712-A2 | New pyrimidine derivatives, processes for preparation thereof and composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |
| US-4532248-A | Administering 1,4-dihydropyridine derivative exhibiting positive inotropic activity | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0059165-B1 | METHOD AND DYESTUFFS FOR DYEING CELLULOSICS AND BLENDS THEREOF WITHOUT AFTERWASH | CIBA-GEIGY AG (CH) | 1985-05-15 | — | — | EP | disclosed |
| EP-0059165-A1 | Method and dyestuffs for dyeing cellulosics and blends thereof without afterwash | CIBA-GEIGY AG (CH) | 1982-09-01 | — | — | EP | disclosed |
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12227524-B2 | Anti-infective compounds | RABGGTB, ELANE, SERPINB1 | LMNA 4132/4885GSK3B 3486/4885MEN1 3685/4885 |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | DHFR, DHPS, MTHFD1 | LMNA 3293/4885GSK3B 3565/4885MEN1 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.