Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638474 | 0.79 | ADRA1D (0.43) | HDAC8ALDH1A1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL28080903 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL28080836 | 0.76 | F2RL3 (0.39) | ALDH1A1LMNA | |
| SCHEMBL28080828 | 0.76 | CCR2 (0.46) | KMT2AMEN1 | |
| SCHEMBL28080966 | 0.74 | GFER (0.46) | HDAC8ALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL28080891 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL28080894 | 0.71 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTTDP1LMNA | |
| SCHEMBL28080843 | 0.71 | CYP11B1 (0.44) | HDAC8ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL1031517 | 0.70 | KDM4E (0.46) | HDAC8ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL27770330 | 0.69 | CHRM1 (0.43) | HDAC8LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823061-A | Pyrrole-2, 5-dione derivatives as liver X receptor modulators | ASTRAZENECA AB (SE) | 2006-08-23 | — | — | CN | disclosed |