Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080836 | 0.90 | F2RL3 (0.39) | ALDH1A1LMNAADRA1DBRD4 | |
| SCHEMBL28080903 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNAADRA1DKDM4ETP53 | |
| SCHEMBL28080828 | 0.86 | CCR2 (0.46) | SIGMAR1CCR2HTT | |
| SCHEMBL28080891 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAADRA1DKDM4EL3MBTL1 | |
| SCHEMBL27962502 | 0.79 | HDAC4 (0.37) | BRD4 | |
| SCHEMBL28080966 | 0.79 | GFER (0.46) | ALDH1A1LMNASIGMAR1SMN1; SMN2 | |
| SCHEMBL28831826 | 0.79 | AR (0.41) | ALDH1A1LMNAADRA1DKDM4ESMN1; SMN2 | |
| SCHEMBL28831769 | 0.79 | GFER (0.46) | ALDH1A1LMNAL3MBTL1SIGMAR1 | |
| SCHEMBL28080843 | 0.79 | CYP11B1 (0.44) | ALDH1A1LMNAKDM4EMAPTHTT | |
| SCHEMBL28831833 | 0.78 | GPR52 (0.40) | ALDH1A1ADRA1DKDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804108-B | A kind of method preparing primary amine | 沈阳药科大学 | 2016-08-03 | — | — | CN | disclosed |