Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080836 | 0.88 | F2RL3 (0.39) | LMNAALDH1A1AR | |
| SCHEMBL28080903 | 0.85 | ALDH1A1 (0.43) | CYP11B1CYP11B2POLBLMNAHTT | |
| SCHEMBL28080966 | 0.81 | GFER (0.46) | CYP11B1CYP11B2POLBLMNAALDH1A1 | |
| SCHEMBL28080828 | 0.81 | CCR2 (0.46) | HTTFAAH | |
| SCHEMBL28080894 | 0.79 | ALDH1A1 (0.47) | LMNAHTTKDM4EALDH1A1MAPT | |
| SCHEMBL28080891 | 0.77 | ALDH1A1 (0.44) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL28831826 | 0.74 | AR (0.41) | POLBLMNAKDM4EALDH1A1AR | |
| SCHEMBL27962502 | 0.74 | HDAC4 (0.37) | HDAC8HDAC6 | |
| SCHEMBL28080830 | 0.74 | TUBB4A (0.46) | POLBALDH1A1 | |
| SCHEMBL28080840 | 0.73 | COMT (0.41) | MAPTHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804108-B | A kind of method preparing primary amine | 沈阳药科大学 | 2016-08-03 | — | — | CN | disclosed |