Methacrylic Acid

Methacrylic Acid

SCHEMBL27650290

C=C(C)C(=O)O.CCC(C)C1CCc2c(ccc3c2ccc2ccccc23)C1

nearest known ligand 0.34

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 3/20 0.34
NFKB2 Q00653 3/20 0.34
RELA Q04206 3/20 0.34
ALDH1A1 P00352 4/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
RCE1 Q9Y256 1/20 0.33
HTR7 P34969 3/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
HPGD P15428 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
ANPEP P15144 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27630245 0.83 LNPEP (0.37) NFKB1NFKB2RELAALDH1A1MAPT
Methacrylic Acid SCHEMBL27650291 0.82 NFKB1 (0.36) NFKB1NFKB2RELAALDH1A1MAPT
Methacrylic Acid SCHEMBL27630262 0.82 CYP1A2 (0.38) NFKB1NFKB2RELAALDH1A1MAPT
Methacrylic Acid SCHEMBL28204534 0.80 HCAR2 (0.36) NFKB1NFKB2RELAALDH1A1MAPT
Methacrylic Acid SCHEMBL27650365 0.80 HTR7 (0.34) NFKB1NFKB2RELAALDH1A1MAPT
Methacrylic Acid SCHEMBL27650287 0.79 MAPT (0.39) NFKB1NFKB2RELAALDH1A1MAPT
Methacrylic Acid SCHEMBL28226348 0.78 CYP1A2 (0.34) NFKB1NFKB2RELAALDH1A1MAPT
Methacrylic Acid SCHEMBL31218471 0.75 ALDH1A1 (0.42) ALDH1A1MAPTKDM4ECYP1A2HPGD
Methacrylic Acid SCHEMBL27340472 0.75 ALDH1A1 (0.42) ALDH1A1MAPTKDM4ECYP1A2HPGD
SCHEMBL28233739 0.73 HPRT1 (0.36) NFKB1NFKB2RELAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100582131-C Fumaric diester copolymer TOSO KK 2010-01-20 CN disclosed
CN-1814639-A Daip TOSO KK (JP) 2006-08-09 CN disclosed