Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649079 | 0.79 | SLC9A1 (0.57) | SLC9A1HPGDALDH1A1MAPTHTT | |
| SCHEMBL27649028 | 0.77 | SOS1 (0.57) | SLC9A1HPGDALDH1A1MAPTHTT | |
| SCHEMBL27669358 | 0.75 | ALDH1A1 (0.59) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL6010133 | 0.72 | SLC9A1 (0.51) | SLC9A1HPGDALDH1A1MAPTHTT | |
| SCHEMBL6010140 | 0.72 | PIK3CA (0.57) | SLC9A1HPGDALDH1A1MAPTHTT | |
| SCHEMBL4943019 | 0.72 | SLC9A1 (0.61) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL27669329 | 0.71 | SLC9A1 (0.50) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL6285036 | 0.70 | CA2 (0.48) | HPGDALDH1A1MAPTHTTKDM4E | |
| SCHEMBL4720637 | 0.70 | SHMT1 (0.56) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL3141863 | 0.70 | HIF1A (0.61) | HPGDMAPTHTTKDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100519544-C | Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them | KOREA INST OF CHEMISTRY KUL KU (KR) | 2009-07-29 | — | — | CN | disclosed |
| CN-1902188-A | Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them | KOREA RES INST CHEM TECH (KR) | 2007-01-24 | — | — | CN | disclosed |