Sugi Predict

Sugi Predict / Compounds / SCHEMBL6285036

SCHEMBL6285036

SCHEMBL6285036

O=C(O)Cc1ccc(CC(=O)O)o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 2/20 0.48
▸ CAMK2A Q9UQM7 1/20 0.48
▸ AKR1B1 P15121 4/20 0.46
▸ PRSS1 P07477 1/20 0.44
▸ TMPRSS15 P98073 1/20 0.44
▸ TDP1 Q9NUW8 4/20 0.43
▸ POLB P06746 3/20 0.43
▸ TSHR P16473 3/20 0.43
▸ MAPT P10636 2/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ RGS12 O14924 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ APEX1 P27695 1/20 0.43
▸ THPO P40225 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ GNAI1 P63096 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27824505 0.95 CA2 (0.44) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL13359173 0.89 CYP2E1 (0.44) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL27472115 0.89 CA2 (0.40) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL7961905 0.89 ALDH1A1 (0.42) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL17537541 0.87 ALDH1A1 (0.58) CA2CAMK2APRSS1TMPRSS15TDP1
SCHEMBL28556412 0.87 ALDH1A1 (0.42) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL17537932 0.87 CA2 (0.43) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL5581578 0.84 LMNA (0.43) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL28016211 0.84 PRSS1 (0.42) CA2CAMK2AAKR1B1PRSS1TMPRSS15
SCHEMBL1912549 0.84 TDP1 (0.67) CA2CAMK2APRSS1TMPRSS15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192525-A Preparation method of bio-based semi-crystalline semi-aromatic furan polyamide 江苏泰阿生物技术有限公司 2025-06-24 — — CN claimed
CN-116284756-B Method for preparing bio-based semi-aromatic polyamide based on micro-reaction device 南京工业大学 2024-05-31 — — CN claimed
CN-116284756-A Method for preparing bio-based semi-aromatic polyamide based on micro-reaction device 南京工业大学 2023-06-23 — — CN claimed
CN-108546224-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-05-27 — — CN claimed
CN-108530243-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-05-27 — — CN claimed
CN-112724392-B Preparation method of bio-based modified polypropylene carbonate and fiber 杭州师范大学 2022-05-27 — — CN claimed
CN-108530244-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-02-11 — — CN claimed
CN-112745499-A Preparation method of bio-based modified transparent polyamide polymer and fiber 杭州师范大学 2021-05-04 — — CN claimed
CN-112724392-A Preparation method of bio-based modified polypropylene carbonate and fiber 杭州师范大学 2021-04-30 — — CN claimed
CN-120192525-A Preparation method of bio-based semi-crystalline semi-aromatic furan polyamide 江苏泰阿生物技术有限公司 2025-06-24 — — CN disclosed
CN-116284756-B Method for preparing bio-based semi-aromatic polyamide based on micro-reaction device 南京工业大学 2024-05-31 — — CN disclosed
CN-116284756-A Method for preparing bio-based semi-aromatic polyamide based on micro-reaction device 南京工业大学 2023-06-23 — — CN disclosed
WO-2023106707-A1 DEGRADABLE POLYESTER RESIN AND MANUFACTURING METHOD THEREOF 코오롱인더스트리 주식회사 2023-06-15 — — WO disclosed
CN-112724392-B Preparation method of bio-based modified polypropylene carbonate and fiber 杭州师范大学 2022-05-27 — — CN disclosed
US-20160215119-A1 TETRAHYDROFURAN DERIVATIVES AND THEIR USE AS PLASTICIZERS BASF SE (DE) 2016-07-28 — — US disclosed
US-20160075671-A1 TETRAHYDROFURAN DERIVATIVES AND USE THEREOF AS PLASTICIZERS BASF SE (DE) 2016-03-17 — — US disclosed
WO-2016022943-A2 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2016-02-11 — — WO disclosed
US-6958395-B2 Method for producing water-soluble saccharide conjugates and saccharide mimetics by Diels-Alder reaction DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) 2005-10-25 — — US disclosed
US-20040059101-A1 Method for producing water-soluble saccharide conjugates and saccharide mimetics by diels-alder reaction DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) 2004-03-25 — — US disclosed
US-3971728-A CALCIUM OR MAGNESIUM IONS, 2,5-DI-CARBOXY OR CARBOXYMETHYL TETRAHYDROFURAN OR SALTS ETHYL CORPORATION (US) 1976-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160215119-A1 TETRAHYDROFURAN DERIVATIVES AND THEIR USE AS PLASTICIZERS DHPS, MTHFD2, TERT CA2 4829/4885CAMK2A 3355/4885AKR1B1 1826/4885
US-20040059101-A1 Method for producing water-soluble saccharide conjugates and saccharide mimetics by diels-alder reaction SI, MAN1B1, SORD CA2 1991/4885CAMK2A 4786/4885AKR1B1 76/4885
US-20160075671-A1 TETRAHYDROFURAN DERIVATIVES AND USE THEREOF AS PLASTICIZERS CBR3, CBR1, TERT CA2 4681/4885CAMK2A 4395/4885AKR1B1 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.