Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | TAS2R8 | Q9NYW2 | 5/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283138 | 0.81 | MEN1 (0.46) | ALDH1A1MEN1KMT2AROCK2CHRM3 | |
| SCHEMBL27677363 | 0.73 | PRMT5 (0.47) | ALDH1A1MEN1KMT2AROCK2CHRM3 | |
| SCHEMBL6253936 | 0.68 | LMNA (0.44) | ALDH1A1MEN1KMT2AKLKB1FAAH | |
| SCHEMBL27445974 | 0.67 | LMNA (0.51) | ALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL27695831 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AROCK2KLKB1 | |
| SCHEMBL7511407 | 0.65 | HTR1A (0.57) | ALDH1A1CHRM3HTR2BHTR1ADRD2 | |
| SCHEMBL27441895 | 0.65 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AROCK2KLKB1 | |
| SCHEMBL27441898 | 0.65 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AROCK2KLKB1 | |
| SCHEMBL6269923 | 0.65 | LMNA (0.45) | ALDH1A1MEN1KMT2AFAAHL3MBTL1 | |
| SCHEMBL27807338 | 0.65 | SLC6A2 (0.53) | HTR2BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023083-A | Nitrogenous fused bicyclic compound | TANABE SEIYAKU CO (JP) | 2007-08-22 | — | — | CN | disclosed |