Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672052 | 0.82 | ADRB1 (0.54) | MEN1KMT2AALDH1A1ADRB1HTR1A | |
| SCHEMBL27677268 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1CHRM3HTR1A | |
| SCHEMBL27677363 | 0.80 | PRMT5 (0.47) | MEN1KMT2AALDH1A1CHRM3HTR1A | |
| SCHEMBL6668632 | 0.80 | HDAC4 (0.40) | MEN1KMT2AALDH1A1ADRB1TSHR | |
| SCHEMBL22957172 | 0.79 | SIGMAR1 (0.50) | ADRB1USP2HTR1AHTR6LMNA | |
| SCHEMBL6922833 | 0.78 | ADRB1 (0.69) | MEN1KMT2AALDH1A1ADRB1CYP1A2 | |
| SCHEMBL27445974 | 0.76 | LMNA (0.51) | MEN1KMT2AALDH1A1USP2TSHR | |
| SCHEMBL6254518 | 0.76 | LMNA (0.51) | MEN1KMT2AALDH1A1USP2CYP1A2 | |
| SCHEMBL27462030 | 0.76 | LMNA (0.51) | MEN1KMT2AALDH1A1USP2CYP1A2 | |
| SCHEMBL6269923 | 0.75 | LMNA (0.45) | MEN1KMT2AALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023083-A | Nitrogenous fused bicyclic compound | TANABE SEIYAKU CO (JP) | 2007-08-22 | — | — | CN | disclosed |
| EP-1585481-A2 | PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004064721-A2 | A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-08-05 | — | — | WO | disclosed |