Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263364 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2ERCC5FEN1KMT2AMEN1 | |
| SCHEMBL11087771 | 0.92 | MMP1 (0.55) | SMN1; SMN2ERCC5FEN1KMT2AMEN1 | |
| SCHEMBL7409439 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2ERCC5FEN1KMT2AMEN1 | |
| SCHEMBL9859579 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2ERCC5FEN1KMT2AMEN1 | |
| SCHEMBL3167665 | 0.86 | MAOB (0.62) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL572 | 0.85 | KMT2A (0.58) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL10596300 | 0.84 | KMT2A (0.65) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11515591 | 0.84 | TSHR (0.66) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8085697 | 0.84 | CA12 (0.61) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL8585196 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105523874-A | Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives | ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV | 2016-04-27 | — | — | CN | claimed |
| CN-105461496-A | Preparation method for 2-halogenated-1,3-dicarbonyl derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-04-06 | — | — | CN | claimed |
| EP-3704094-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-3551183-B1 | INHIBITORS OF MECHANOTRANSDUCTION TO TREAT PAIN AND MODULATE TOUCH PERCEPTION | MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN HELMHOLTZ GEMEINSCHAFT (DE) | 2025-08-20 | — | — | EP | disclosed |
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-118891042-A | Viral helicase inhibitors binding to novel allosteric binding sites | 艾斯巴赫生物有限公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-3962915-B1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2024-09-04 | — | — | EP | disclosed |
| EP-4422619-A1 | INHIBITORS OF VIRAL HELICASES BINDING TO A NOVEL ALLOSTERIC BINDING SITE | Eisbach Bio GmbH (DE) | 2024-09-04 | — | — | EP | disclosed |
| US-20240166652-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ABBVIE INC. | 2024-05-23 | — | — | US | disclosed |
| CN-117624168-A | Condensed ring heterocyclic compound and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2024024760-A1 | PYRAZOLONE COMPOUND AND PYRAZOLONE AGENT | 公益財団法人野口研究所 | 2024-02-01 | — | — | WO | disclosed |
| US-4248961-A | YELLOW COUPLER ACHIEVING GOOD COLOR DENSITY | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4222739-A | Certain bis(phenyl)-benzodifurans | CIBA-GEIGY CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4129738-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-12-12 | — | — | US | disclosed |
| US-4048184-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4042702-A | ANALGESIC, ANTIPYRETIC, ANTIPHLOGISTIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-08-16 | — | — | US | disclosed |
| US-4028381-A | ANTIANXIETY AND ANTIDEPRESSANT AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
| US-4022801-A | ANTIANXIETY AND ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-3974176-A | ANALGESIC, ANTIPYRETIC, ANTIPHLOGISTIC | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3969368-A | 2-Substituted benzodioxoles | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166652-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ATF4, ATF1, DDIT3 | SMN1; SMN2 2486/4885ERCC5 1163/4885FEN1 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.