SCHEMBL27709458

SCHEMBL27709458

CCc1cc(CC)n(CCOC(C)=O)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
ADORA2B P29275 2/20 0.35
TSHR P16473 2/20 0.34
SLC18A3 Q16572 1/20 0.34
CRHR1 P34998 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
IDO1 P14902 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RET P07949 1/20 0.33
PRKX P51817 1/20 0.33
TAOK1 Q7L7X3 1/20 0.33
GAA P10253 1/20 0.33
SMYD3 Q9H7B4 1/20 0.32
CA12 O43570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28311236 0.78 MPO (0.38) ALDH1A1CRHR1KDM4EMEN1KMT2A
SCHEMBL28310677 0.74 HCAR3 (0.35) ALDH1A1CRHR1KDM4EHTTCA12
SCHEMBL18198140 0.74 ADORA2A (0.41) ADORA2BCRHR1CA12CA1CA2
SCHEMBL28310494 0.73 CA12 (0.32) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL2587727 0.71 LMNA (0.49) ALDH1A1CRHR1TDP1GAACA12
SCHEMBL27771434 0.71 KDM4E (0.55) ALDH1A1TSHRKDM4EMAPTHTT
SCHEMBL27811680 0.69 ADORA2B (0.44) ALDH1A1ADORA2BTSHRSLC18A3KDM4E
SCHEMBL27790378 0.69 CPB2 (0.47) ALDH1A1ADORA2BTSHRSLC18A3L3MBTL1
SCHEMBL22695701 0.69 ALOX5 (0.42) ALDH1A1ADORA2B
SCHEMBL29209455 0.69 ALDH1A1 (0.45) ALDH1A1TSHRKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101228156-A Fungicidal carboxamides DU PONT (US) 2008-07-23 CN disclosed