Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545527 | 0.81 | TTK (0.48) | AKR1B1HTR6ABCB1ABCC1NLRP3 | |
| SCHEMBL2017604 | 0.78 | CSNK2A1 (0.33) | CSNK2A1 | |
| Piperazine SCHEMBL1544743 | 0.75 | TTK (0.43) | AKR1B1HTR6TTKALDH1A1KDM4E | |
| SCHEMBL27716472 | 0.72 | AKR1B1 (0.40) | AKR1B1HTR6ABCB1ABCC1NLRP3 | |
| SCHEMBL2299132 | 0.71 | KIF11 (0.44) | AKR1B1HTR6ABCB1ABCC1NLRP3 | |
| SCHEMBL694496 | 0.71 | ALDH1A1 (0.61) | TTKALDH1A1KDM4EGAAALPL | |
| SCHEMBL13721413 | 0.70 | ATM (0.51) | AKR1B1HTR6ALDH1A1KDM4EGAA | |
| SCHEMBL6977741 | 0.70 | IDO1 (0.52) | AKR1B1TTKALDH1A1KDM4EGAA | |
| SCHEMBL4636341 | 0.69 | HTR6 (0.52) | HTR6TTK | |
| SCHEMBL27737425 | 0.69 | ALDH1A1 (0.38) | AKR1B1HTR6TTKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282938-A | Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2008-10-08 | — | — | CN | claimed |
| CN-101282938-A | Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2008-10-08 | — | — | CN | disclosed |