Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | GYS1 | P13807 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988913 | 0.78 | IMPDH2 (0.56) | IDO1CTSVCTSLMMP2MMP9 | |
| SCHEMBL16454839 | 0.78 | ESR1 (0.67) | IDO1MAPTFASNMEN1KMT2A | |
| Carbazole SCHEMBL27552113 | 0.75 | CTSV (0.67) | IDO1CTSVCTSLMMP2MMP9 | |
| SCHEMBL3881804 | 0.74 | MAP2 (0.69) | IDO1CTSVCTSLMAPTPARP1 | |
| SCHEMBL27214760 | 0.73 | ALDH1A1 (0.56) | MAPTPARP1TNKSGUSBNLRP3 | |
| SCHEMBL28391349 | 0.71 | ESR1 (0.55) | CTSVCTSLMAPTFASN | |
| SCHEMBL9666436 | 0.71 | ALDH1A1 (0.65) | MMP2MMP9MMP8MAPTFASN | |
| Carbazole SCHEMBL28060913 | 0.70 | ALDH1A1 (0.64) | IDO1CTSVCTSLMMP2MMP9 | |
| SCHEMBL8986944 | 0.70 | SMN1; SMN2 (0.66) | IDO1CTSVCTSLMMP2MMP9 | |
| SCHEMBL28072347 | 0.70 | PTGS2 (0.53) | IDO1MAPTKMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101083985-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2007-12-05 | — | — | CN | disclosed |