Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512381 | 0.73 | — | — | |
| SCHEMBL65897 | 0.70 | — | — | |
| SCHEMBL4342803 | 0.65 | MAT2A (0.36) | GAA | |
| Flucytosine SCHEMBL3863945 | 0.63 | ALDH1A1 (0.31) | — | |
| Sulfuric Acid SCHEMBL28173989 | 0.63 | ATAD2 (0.31) | — | |
| SCHEMBL27533747 | 0.61 | — | — | |
| SCHEMBL17077972 | 0.58 | GRIA1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27833004 | 0.58 | GAA (0.32) | HSD17B10GAA | |
| SCHEMBL3634528 | 0.57 | CA5A (0.36) | CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL4970668 | 0.57 | CA2 (0.33) | CYP1A2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268074-B | 5-amino-4-hydroxy-7- (imidazo [1,2-A] pyridin-6- ylmethyl)-8-methyl-nonamide derivatives and related compounds as renin inhibitors for the treatment of hypertension | SPEEDEL EXPERIMENTA AG | 2011-09-21 | — | — | CN | disclosed |
| CN-101268074-A | 5-amino-4-hydroxy-7- (imidazo [1,2-A] pyridin-6- ylmethyl)-8-methyl-nonamide derivatives and related compounds as renin inhibitors for the treatment of hypertension | SPEEDEL EXPERIMENTA AG (CH) | 2008-09-17 | — | — | CN | disclosed |
| CN-101171230-A | Heterocyclic-substituted alkanamides useful as renin inhibitors | SPEEDEL EXPERIMENTA AG (CH) | 2008-04-30 | — | — | CN | disclosed |