Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730382 | 0.92 | C5AR1 (0.39) | LMNAMEN1KMT2AMAPTHTT | |
| SCHEMBL3583039 | 0.88 | CNR1 (0.43) | LMNAMEN1KMT2AMAPTCNR1 | |
| SCHEMBL3580698 | 0.82 | C5AR1 (0.44) | LMNAMEN1KMT2ACNR1SMN1; SMN2 | |
| SCHEMBL27750967 | 0.81 | S1PR1 (0.39) | LMNAMEN1KMT2ACNR1SMN1; SMN2 | |
| SCHEMBL3577052 | 0.80 | C5AR1 (0.37) | LMNAMEN1KMT2AMAPTCNR1 | |
| SCHEMBL3578978 | 0.79 | CNR1 (0.43) | LMNAMEN1KMT2ACNR1SMN1; SMN2 | |
| SCHEMBL3574236 | 0.77 | LMNA (0.40) | LMNAMEN1KMT2AMAPTCNR1 | |
| SCHEMBL3583628 | 0.77 | MCL1 (0.40) | LMNAMEN1KMT2ACNR1SMN1; SMN2 | |
| SCHEMBL3581360 | 0.77 | MCL1 (0.40) | LMNAMEN1KMT2ACNR1SMN1; SMN2 | |
| SCHEMBL3587595 | 0.76 | C5AR1 (0.49) | LMNAMEN1KMT2ACNR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379036-B | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |
| CN-101379036-A | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE (CH) | 2009-03-04 | — | — | CN | disclosed |