SCHEMBL2773099

SCHEMBL2773099

O=C(c1ccccc1)P(=O)(c1ccccc1)c1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 2/20 0.40
HNF4A P41235 1/20 0.39
HDAC8 Q9BY41 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
KMO O15229 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
BCAT2 O15382 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
MEN1 O00255 1/20 0.36
PTPN1 P18031 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2771670 0.90 NR1H4 (0.40) ALDH1A1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL2687995 0.87 PTPN1 (0.41) ALDH1A1KMT2AHDAC8TDP1L3MBTL1
SCHEMBL31401985 0.83 BCAT2 (0.41) ALDH1A1KMT2AHNF4ATDP1L3MBTL1
SCHEMBL58814 0.80 ALDH1A1 (0.52) ALDH1A1KMT2AHDAC8TDP1L3MBTL1
SCHEMBL989034 0.78 HPGD (0.46) ALDH1A1KMT2ATDP1L3MBTL1ATM
SCHEMBL2773100 0.77 FOLH1 (0.46) ALDH1A1KMT2AHNF4AHDAC8BCAT2
SCHEMBL22083769 0.77 RAB9A (0.52) ALDH1A1KMT2AL3MBTL1ATMNPC1
SCHEMBL17446544 0.76 CA2 (0.48) ALDH1A1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL29105784 0.74 MCL1 (0.44) KMT2AMEN1
SCHEMBL4181722 0.74 BCAT2 (0.53) ALDH1A1KMT2AHNF4ABCAT2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723445-B2 Curable resin composition, molded product, and process for producing the same SHOWA HIGHPOLYMER CO., LTD. (JP) 2010-05-25 US disclosed
US-20090008834-A1 Curable resin composition, molded product, and process for producing the same SHOWA HIGHPOLYMER CO., LTD. (JP) 2009-01-08 US disclosed
EP-1785440-A1 CURABLE RESIN COMPOSITION, SHAPED ARTICLE AND METHOD FOR PRODUCING SAME Showa Highpolymer Co., Ltd. (JP) 2007-05-16 EP disclosed