Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714790 | 0.85 | HPGD (0.38) | HSD17B10HTTHPGDKMT2AMEN1 | |
| SCHEMBL27735688 | 0.76 | ELANE (0.41) | KMT2AMEN1LMNAL3MBTL1KDM4E | |
| SCHEMBL1638943 | 0.75 | MAPK8 (0.46) | HSD17B10HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1638027 | 0.71 | KMO (0.40) | HSD17B10HTTHPGDKMT2AMEN1 | |
| SCHEMBL27735636 | 0.65 | L3MBTL1 (0.46) | KMT2AMEN1LMNAL3MBTL1KDM4E | |
| SCHEMBL19250755 | 0.63 | NPC1 (0.32) | HSD17B10HTTHPGDKMT2AMEN1 | |
| SCHEMBL14620917 | 0.63 | ALOX15 (0.50) | HSD17B10HTTHPGDKMT2AMEN1 | |
| SCHEMBL27746406 | 0.63 | BCHE (0.39) | ALDH1A1RAB9A | |
| SCHEMBL27714808 | 0.61 | ELANE (0.40) | KMT2AMEN1L3MBTL1KDM4EKDM4A | |
| SCHEMBL27746408 | 0.61 | ALDH1A1 (0.36) | HSD17B10HTTHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242839-A | Azaindazole compounds and methods of use | CHEMOCENTRYX INC (US) | 2008-08-13 | — | — | CN | disclosed |