SCHEMBL277408

SCHEMBL277408

C=CC(Br)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TRPA1 O75762 1/20 0.41
TSHR P16473 2/20 0.38
DPP4 P27487 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 1/20 0.38
F2 P00734 1/20 0.38
CYP3A4 P08684 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
TAAR1 Q96RJ0 2/20 0.35
HTR2A P28223 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.33
SRC P12931 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7938802 0.97 CES2 (0.39) CES2CES1TRPA1TSHRDPP4
SCHEMBL7131921 0.86 CYP2C19 (0.30) CYP2C19
SCHEMBL7131926 0.77 CYP2C19 (0.42) ALDH1A1CYP2C19CYP3A4MAPTALOX15
SCHEMBL9634797 0.76 ALDH1A1 (0.36) TSHRALDH1A1CYP2C19
SCHEMBL5134897 0.75 ALDH1A1 (0.52) TSHRALDH1A1
SCHEMBL11210246 0.75 CHRNA7 (0.39) ALDH1A1CYP2C19CYP3A4KDM4EMAPT
SCHEMBL28760656 0.75
SCHEMBL688950 0.74 CES2 (0.46) CES2CES1TRPA1TSHRDPP4
SCHEMBL1176831 0.74 CES2 (0.41) CES2CES1TRPA1TSHRDPP4
SCHEMBL11331307 0.74 CES2 (0.41) CES2CES1TRPA1TSHRDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 673 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077540-B1 POLYESTER COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2026-05-13 EP claimed
US-12507695-B2 Quaternary ammonium organosilane hydrolysate and a method for preparing same SABANCI UNIVERSITESI (TR) 2025-12-30 US claimed
CN-114829499-B Polyester composition SABIC环球技术有限责任公司 2024-07-26 CN claimed
CN-114846081-B Polyolefin/polyester resin SABIC环球技术有限责任公司 2024-02-02 CN claimed
CN-117229301-A Spirofluorene functionalized near infrared two-region fluorescent dye, synthesis method and application 南京信息工程大学 2023-12-15 CN claimed
EP-4125383-B1 A STABLE AQUEOUS FORMULATION CONTAINING QUATERNARY AMMONIUM ORGANOSILANE HYDROLYSATE AND A METHOD FOR PREPARING SAME UNIV SABANCI (TR) 2023-10-18 EP claimed
CN-108794338-B Method for preparing dialkyl diphenylamine by adopting C-N coupling reaction 中国机械总院集团武汉材料保护研究所有限公司 2023-07-25 CN claimed
US-20230104765-A1 STABLE AQUEOUS FORMULATION CONTAINING QUATERNARY AMMONIUM ORGANOSILANE HYDROLYSATE AND A METHOD FOR PREPARING SAME SABANCI UNIVERSITESI (TR) 2023-04-06 US claimed
EP-4125383-A1 A STABLE AQUEOUS FORMULATION CONTAINING QUATERNARY AMMONIUM ORGANOSILANE HYDROLYSATE AND A METHOD FOR PREPARING SAME Sabanci Üniversitesi (TR) 2023-02-08 EP claimed
EP-4077538-A1 POLYOLEFIN/POLYESTER RESIN SABIC Global Technologies B.V. (NL) 2022-10-26 EP claimed
US-4707558-A USING A POLAR APPOTIC SOLVENT TO REACT AN ALKALI METAL PHENOXIDE BASED ON A POLYHYDROXY COMPOUND WITH A VINYLBENZYL HALIDE THE DOW CHEMICAL COMPANY (US) 1987-11-17 US claimed
EP-0052854-B1 POLYPHENYLENE OXIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-07-02 EP claimed
EP-0036528-B1 BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-01-16 EP claimed
US-4423198-A WITH POLYMERIZABLE TERTIARY AMINE AND CROSSLINKER COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1983-12-27 US claimed
EP-0052854-A1 Polyphenylene oxide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-02 EP claimed
US-4048261-A Vulcanizable compositions of a halogen-containing polymer and a diene-nitrile rubber having active halogen cure sites THE B. F. GOODRICH COMPANY (US) 1977-09-13 US claimed
US-4036886-A FROM A PHENYL ALKENYL BROMIDE AND LITHIUM SALT OF A SCHIFF BASE OF ACETALDEHYDE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-07-19 US claimed
US-3976625-A NITRILE POLYMERS HAVING ACTIVE HALOGEN SITES THE B.F. GOODRICH COMPANY (US) 1976-08-24 US claimed
US-3976610-A Acrylate rubber vulcanizable compositions THE B. F. GOODRICH COMPANY (US) 1976-08-24 US claimed
US-3935136-A SUSPENSION POLYMERIZATION, CROSSLINKING PHILLIPS PETROLEUM COMPANY (US) 1976-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507695-B2 Quaternary ammonium organosilane hydrolysate and a method for preparing same SI, EPN1, ESYT1 CES2 243/4885CES1 184/4885TRPA1 3041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.