Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246785 | 0.86 | ACP3 (0.44) | CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL21495038 | 0.81 | LTA4H (0.46) | TSHRLMNAKMT2A | |
| SCHEMBL1420027 | 0.81 | RXRA (0.41) | CES2CES1LMNAKMT2A | |
| SCHEMBL1701352 | 0.81 | LTA4H (0.46) | TSHRLMNAKMT2A | |
| SCHEMBL15229334 | 0.80 | HTR6 (0.52) | TSHRALDH1A1KMT2A | |
| SCHEMBL4329868 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL579790 | 0.79 | ACP3 (0.31) | — | |
| SCHEMBL1440680 | 0.79 | ACP3 (0.31) | — | |
| SCHEMBL22590138 | 0.77 | CYP2A6 (0.40) | CES2CES1ALDH1A1CYP2A6MAPK1 | |
| SCHEMBL321965 | 0.77 | CYP2A6 (0.40) | CES2CES1ALDH1A1CYP2A6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986200-A | Preparation method of phenyl-dithiazole derivative | 烟台新药创制山东省实验室 | 2024-05-07 | — | — | CN | claimed |
| CN-111233908-A | Benzoxaborol-1-ol compound and preparation method and application thereof | 南京农业大学 | 2020-06-05 | — | — | CN | claimed |
| JP-57134417-A | — | — | None | — | — | JP | disclosed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | disclosed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230019129-A1 | HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2023-01-19 | — | — | US | disclosed |
| US-20220332695-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RESEARCH TRIANGLE INSTITUTE | 2022-10-20 | — | — | US | disclosed |
| CN-114804988-A | Method for synthesizing brominated organic compound through oxygen oxidation bromination with controllable chemical selectivity | 杭州医学院 | 2022-07-29 | — | — | CN | disclosed |
| EP-3990112-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RTI International (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-114269719-A | Urea derivatives as CB1 allosteric modulators | RTI国际 | 2022-04-01 | — | — | CN | disclosed |
| EP-3974426-A1 | HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS | Indiana University Research and Technology Corporation (US) | 2022-03-30 | — | — | EP | disclosed |
| EP-0505111-A2 | Angiotensin II antagonists incorporating a substituted imidazo (1,2-b)(1,2,4) triazole | MERCK & CO. INC. (US) | 1992-09-23 | — | — | EP | disclosed |
| EP-0283390-A2 | Thiazole derivatives active on the cholinergic system, process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1988-09-21 | — | — | EP | disclosed |
| US-4687775-A | ANTIULCER AGENTS | G. D. SEARLE & CO. (US) | 1987-08-18 | — | — | US | disclosed |
| US-4656290-A | Process for preparing thio, dithio or carbonyl compounds | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1987-04-07 | — | — | US | disclosed |
| EP-0150026-A2 | Chemical process | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1985-07-31 | — | — | EP | disclosed |
| US-4418070-A | 5-PHENYL-THIAZOLES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1983-11-29 | — | — | US | disclosed |
| JP-S57134417-A | CARDIOTONIC AGENT | MEIJI SEIKA KAISHA LTD | 1982-08-19 | — | — | JP | disclosed |
| US-4197306-A | CONTROL OF INSECTS AND ACARIDS | UNIROYAL, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019129-A1 | HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS | HAVCR2, MAVS, FABP1 | CES2 1612/4885CES1 221/4885CYP2D6 1475/4885 |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | NAMPT, NAPRT, NNT | CES2 2195/4885CES1 1702/4885CYP2D6 4390/4885 |
| US-20220332695-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | CNR1, CNR2, GPR119 | CES2 71/4885CES1 136/4885CYP2D6 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.