Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22499185 | 0.79 | TDP1 (0.58) | TDP1L3MBTL1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL502066 | 0.78 | TDP1 (0.45) | TDP1L3MBTL1SMN1; SMN2IDO1CYP2C19 | |
| SCHEMBL20673370 | 0.75 | ALDH1A1 (0.50) | TDP1L3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20869833 | 0.75 | SMN1; SMN2 (0.48) | TDP1L3MBTL1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16217874 | 0.75 | ALDH1A1 (0.50) | TDP1L3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6937307 | 0.75 | SMN1; SMN2 (0.67) | L3MBTL1SMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL26315892 | 0.74 | ALDH1A1 (0.49) | TDP1L3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1524413 | 0.74 | CA12 (0.47) | TDP1L3MBTL1IDO1ALDH1A1LMNA | |
| SCHEMBL8003191 | 0.74 | KMT2A (0.41) | TDP1L3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20113451 | 0.73 | L3MBTL1 (0.53) | TDP1L3MBTL1IDO1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101415839-B | Method for sequencing a polynucleotide template | SOLEXA LTD | 2012-06-27 | — | — | CN | disclosed |
| CN-101415839-A | Method for sequencing a polynucleotide template | SOLEXA LTD (GB) | 2009-04-22 | — | — | CN | disclosed |