Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760596 | 0.78 | MAPK14 (0.52) | MAPK14KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL1336997 | 0.70 | MAPK14 (0.49) | MAPK14KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL9301103 | 0.68 | MAPK14 (0.56) | MAPK14KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL4760637 | 0.67 | SRC (0.48) | MAPK14KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL4760559 | 0.66 | KMT2A (0.44) | MAPK14KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL9302124 | 0.65 | L3MBTL1 (0.59) | MAPK14KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15024745 | 0.63 | GPR3 (0.64) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9299635 | 0.62 | MAPK14 (0.56) | MAPK14KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL9301200 | 0.61 | ELANE (0.53) | MAPK14KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8948131 | 0.60 | TACR1 (0.55) | MAPK14KMT2ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101312970-A | 6-heteroaryl pyridoindolone derivatives, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2008-11-26 | — | — | CN | disclosed |