Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768902 | 0.84 | ALDH1A1 (0.54) | MCL1ALDH1A1TSHRPOLBMAPT | |
| SCHEMBL22928132 | 0.82 | ALDH1A1 (0.41) | MCL1ALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL15714285 | 0.81 | KIF11 (0.50) | ALDH1A1GAATSHRMAPTCYP1A2 | |
| SCHEMBL1133023 | 0.80 | MCL1 (0.51) | MCL1ALDH1A1ADRA2ALMNASMN1; SMN2 | |
| SCHEMBL11055193 | 0.80 | MCL1 (0.54) | MCL1ALDH1A1ADRA2AGAALMNA | |
| SCHEMBL17671209 | 0.80 | HDAC1 (0.54) | MCL1ALDH1A1LMNASMN1; SMN2CHRNA7 | |
| SCHEMBL3232155 | 0.79 | LMNA (0.58) | MCL1ALDH1A1LMNAPOLBMAPT | |
| Ammonia Solution, Strong SCHEMBL3234716 | 0.78 | LMNA (0.57) | MCL1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL13451876 | 0.78 | CHRNA7 (0.64) | ALDH1A1GAALMNATSHRSMN1; SMN2 | |
| SCHEMBL9226616 | 0.78 | TAS2R14 (0.50) | MCL1GAATSHRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2017-07-27 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2543670-B1 | PYRAZOLOPYRIMIDIN-DERIVATIVE FÜR DIE BEHANDLUNG VON HAUTKRANKHEITEN | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-20160008362-A1 | AGENT FOR PREVENTING AND/OR TREATING OCULAR INFLAMMATORY DISEASE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-01-14 | — | — | US | disclosed |
| US-8946266-B2 | Substituted triazole and imidazole derivatives as gamma secretase modulators | Janssen Pharmaceuticals, Inc. (US) | 2015-02-03 | — | — | US | disclosed |
| US-8946266-B2 | Substituted triazole and imidazole derivatives as gamma secretase modulators | Janssen Pharmaceuticals, Inc. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140221340-A1 | CHEMOKINE RECEPTOR ACTIVITY REGULATOR | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20120135981-A1 | NOVEL SUBSTITUTED TRIAZOLE AND IMIDAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS | CELLZOME LIMITED (GB) | 2012-05-31 | — | — | US | disclosed |
| US-20120135981-A1 | NOVEL SUBSTITUTED TRIAZOLE AND IMIDAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS | CELLZOME LIMITED (GB) | 2012-05-31 | — | — | US | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |
| WO-2011108689-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | 協和発酵キリン株式会社 (JP) | 2011-09-09 | — | — | WO | disclosed |
| CN-101437804-A | Dibenzyl amine compounds and derivatives | PFIZER PROD INC (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-101437803-A | Dibenzyl amine derivatives as CETP inhibitors | PFIZER PROD INC (US) | 2009-05-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MCL1 4850/4885ALDH1A1 3579/4885ADRA2A 733/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | MCL1 4859/4885ALDH1A1 3568/4885ADRA2A 686/4885 |
| US-20140221340-A1 | CHEMOKINE RECEPTOR ACTIVITY REGULATOR | CXCR2, ACKR3, CCR2 | MCL1 1733/4885ALDH1A1 1287/4885ADRA2A 801/4885 |
| US-20160008362-A1 | AGENT FOR PREVENTING AND/OR TREATING OCULAR INFLAMMATORY DISEASE | NR0B1, NR2E3, NR0B2 | MCL1 4688/4885ALDH1A1 1026/4885ADRA2A 409/4885 |
| US-20120135981-A1 | NOVEL SUBSTITUTED TRIAZOLE AND IMIDAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS | BACE1, BACE2, APH1A | MCL1 2309/4885ALDH1A1 1231/4885ADRA2A 429/4885 |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | OR51E2, TRPA1, OR10J3 | MCL1 4856/4885ALDH1A1 3549/4885ADRA2A 717/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MCL1 4850/4885ALDH1A1 3579/4885ADRA2A 733/4885 |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MCL1 4861/4885ALDH1A1 3533/4885ADRA2A 661/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MCL1 4859/4885ALDH1A1 3568/4885ADRA2A 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.