Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28783978 | 0.78 | MMP2 (0.49) | MMP2KMT2APKMALDH1A1HTR2A | |
| SCHEMBL4423862 | 0.78 | MMP2 (0.53) | MMP2KMT2APKMALDH1A1HTR2A | |
| SCHEMBL8740500 | 0.78 | MMP2 (0.53) | MMP2KMT2APKMALDH1A1HTR2A | |
| SCHEMBL2387943 | 0.78 | MMP2 (0.53) | MMP2KMT2APKMALDH1A1HTR2A | |
| Lysine SCHEMBL28327845 | 0.76 | GSR (0.56) | MMP2KMT2APKMALDH1A1MAPT | |
| Lysine SCHEMBL28385610 | 0.76 | GSR (0.56) | MMP2KMT2APKMALDH1A1MAPT | |
| SCHEMBL14125570 | 0.76 | MGLL (0.46) | KMT2APKMALDH1A1HTR2ABCL9 | |
| Lysine SCHEMBL27760106 | 0.75 | GSR (0.54) | MMP2KMT2APKMALDH1A1MAPT | |
| Lysine SCHEMBL27760108 | 0.75 | GSR (0.54) | MMP2KMT2APKMALDH1A1MAPT | |
| SCHEMBL14308548 | 0.73 | KMT2A (0.73) | KMT2APKMALDH1A1HTR2ABCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522249-C | Elongated multiple spacers in activatable prodrugs | SINTAGAR B V (NL) | 2009-08-05 | — | — | CN | disclosed |