Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387943 | 0.90 | MMP2 (0.53) | MMP2HTR2AMAPTCRHBPCRHR2 | |
| SCHEMBL8740500 | 0.90 | MMP2 (0.53) | MMP2HTR2AMAPTCRHBPCRHR2 | |
| SCHEMBL4423862 | 0.90 | MMP2 (0.53) | MMP2HTR2AMAPTCRHBPCRHR2 | |
| SCHEMBL6245105 | 0.84 | DPP8 (0.50) | MMP2HTR2AMC4RDPP8DPP9 | |
| SCHEMBL27760603 | 0.78 | MMP2 (0.48) | MMP2HTR2AMAPTCRHBPCRHR2 | |
| SCHEMBL15810831 | 0.78 | LTA4H (0.57) | MMP2HTR2AMAPTL3MBTL1KMT2A | |
| SCHEMBL7874885 | 0.78 | LTA4H (0.41) | MMP2HTR2AL3MBTL1KMT2ADPP8 | |
| SCHEMBL8574344 | 0.75 | MMP2 (0.56) | MMP2GAAMC4RALDH1A1PDF | |
| SCHEMBL3176066 | 0.75 | GAA (0.61) | HTR2AMAPTBCL9CTNNB1KMT2A | |
| SCHEMBL18941468 | 0.75 | PDF (0.48) | MMP2HTR2AMAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522249-C | Elongated multiple spacers in activatable prodrugs | SINTAGAR B V (NL) | 2009-08-05 | — | — | CN | disclosed |