Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057305 | 0.98 | ALDH1A1 (0.60) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL16236848 | 0.98 | ALDH1A1 (0.60) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL16236793 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL965056 | 0.92 | TSHR (0.65) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL965573 | 0.92 | TSHR (0.65) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL16236555 | 0.92 | ALDH1A1 (0.73) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL965893 | 0.92 | TSHR (0.65) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL16237314 | 0.92 | ALDH1A1 (0.73) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL24735755 | 0.91 | TSHR (0.79) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| Magnesium Chloride Anhydrous SCHEMBL28044649 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP3A4LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160096819-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2016-04-07 | — | — | US | claimed |
| EP-2997020-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2016-03-23 | — | — | EP | claimed |
| CN-105189477-A | Process for preparing n-substituted 1h-pyrazole-5-carboxylic acid compounds and derivatives thereof | BASF SE | 2015-12-23 | — | — | CN | claimed |
| WO-2014184343-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2014-11-20 | — | — | WO | claimed |
| EP-4532642-B1 | NEW LOW VISCOSITY FUNCTIONAL FLUIDS | BASF SE (DE) | 2026-04-22 | — | — | EP | disclosed |
| EP-4532642-A1 | NEW LOW-VISCOSITY FUNCTIONAL LIQUIDS | BASF SE (DE) | 2025-04-09 | — | — | EP | disclosed |
| CN-115003775-B | Colorant for heat transfer fluid and composition containing same | KD精细化工有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114787288-B | Colorant for heat transfer fluid and composition containing same | KD精细化工有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023232577-A1 | NEW LOW-VISCOSITY FUNCTIONAL LIQUIDS | BASF SE (DE) | 2023-12-07 | — | — | WO | disclosed |
| EP-4286497-A1 | NEW LOW VISCOSITY FUNCTIONAL FLUIDS | BASF SE (DE) | 2023-12-06 | — | — | EP | disclosed |
| US-20230053517-A1 | COLORANT FOR HEAT TRANSFER FLUID, AND COMPOSITION COMPRISING SAME | KD FINECHEM CO., LTD. (KR) | 2023-02-23 | — | — | US | disclosed |
| US-20220363697-A1 | COLORANT FOR HEAT TRANSFER FLUID, AND COMPOSITION COMPRISING SAME | KD FINECHEM CO., LTD. (KR) | 2022-11-17 | — | — | US | disclosed |
| US-20080027068-A1 | HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES LIMITED (JP) | 2008-01-31 | — | — | US | disclosed |
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| EP-1819692-A1 | 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2007-08-22 | — | — | EP | disclosed |
| CN-1798739-A | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD (JP) | 2006-07-05 | — | — | CN | disclosed |
| WO-2006062240-A1 | 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-06-15 | — | — | WO | disclosed |
| US-20060094694-A1 | Heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES LIMITED (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094694-A1 | Heterocyclic compounds and thrombopoietin receptor activators | NR2C2, ROR1, NR0B2 | ALDH1A1 3160/4885TSHR 47/4885CYP3A4 337/4885 |
| US-20080027068-A1 | HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NR2C2, ROR1, NR0B2 | ALDH1A1 3206/4885TSHR 44/4885CYP3A4 353/4885 |
| US-20220363697-A1 | COLORANT FOR HEAT TRANSFER FLUID, AND COMPOSITION COMPRISING SAME | TRMT1, GFPT1, TRMT1L | ALDH1A1 574/4885TSHR 4672/4885CYP3A4 1082/4885 |
| US-20160096819-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | CA3, CA2, CA1 | ALDH1A1 989/4885TSHR 959/4885CYP3A4 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.