SCHEMBL2776767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18355103	0.93	EDNRB (0.40)	TAS1R3TAS1R1POLBALDH1A1TSHR
	SCHEMBL9610453	0.89	TAS1R3 (0.36)	TAS1R3TAS1R1POLBGAAALDH1A1
	SCHEMBL9891412	0.86	CYP3A4 (0.40)	TAS1R3TAS1R1POLBGAAALDH1A1
	SCHEMBL9610480	0.85	TAS1R3 (0.46)	TAS1R3TAS1R1MEN1KMT2AHDAC4
	SCHEMBL21778844	0.81	F2 (0.50)	POLBGAAALDH1A1TSHRLMNA
	SCHEMBL21758200	0.80	LMNA (0.46)	POLBGAAALDH1A1TSHRLMNA
	SCHEMBL18355102	0.80	MAPT (0.38)	TAS1R3TAS1R1ALDH1A1KDM4ELMNA
	SCHEMBL17995090	0.80	MAPT (0.38)	TAS1R3TAS1R1POLBALDH1A1TSHR
	SCHEMBL9610448	0.79	SMN1; SMN2 (0.37)	GAAALDH1A1KDM4ELMNAMEN1
	SCHEMBL18826446	0.77	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.