Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691392 | 0.86 | CA2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL28114539 | 0.82 | RAB9A (0.53) | POLBRAB9A | |
| SCHEMBL27789789 | 0.79 | RAB9A (0.46) | POLBRAB9A | |
| SCHEMBL27789664 | 0.78 | MAPT (0.48) | POLBRAB9A | |
| SCHEMBL28784637 | 0.78 | LTA4H (0.51) | POLBRAB9A | |
| SCHEMBL7458329 | 0.74 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL28784634 | 0.74 | LMNA (0.50) | POLBRAB9A | |
| SCHEMBL28562593 | 0.73 | SMN1; SMN2 (0.54) | POLBRAB9A | |
| SCHEMBL25337392 | 0.73 | MAPT (0.51) | POLBRAB9A | |
| SCHEMBL25336331 | 0.73 | MKNK2 (0.43) | POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100572381-C | Pyrazolonaphthyridine derivative | ASKA PHARM CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |