Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 10/20 | 0.41 |
| ▸ | DRD2 | P14416 | 10/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | DRD5 | P21918 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768152 | 0.91 | DRD3 (0.42) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL27747005 | 0.89 | BCL9 (0.40) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL3939609 | 0.83 | DRD3 (0.45) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL27768051 | 0.82 | BCL9 (0.39) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL3943769 | 0.81 | DRD2 (0.45) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL28781341 | 0.80 | L3MBTL1 (0.39) | BCL9CTNNB1 | |
| SCHEMBL27746990 | 0.79 | ALDH1A1 (0.39) | DRD3DRD2DRD4DRD1DRD5 | |
| Ethylbenzene SCHEMBL27747313 | 0.79 | ALDH1A1 (0.40) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL3930618 | 0.77 | ALDH1A1 (0.53) | BCL9CTNNB1 | |
| SCHEMBL27768143 | 0.77 | DRD2 (0.37) | DRD3DRD2DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |