Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7868700 | 0.96 | ALDH1A1 (0.33) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL458918 | 0.94 | GLRA1 (0.35) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| Oxalic Acid SCHEMBL2876245 | 0.84 | FDPS (0.32) | — | |
| SCHEMBL2776898 | 0.77 | FDPS (0.35) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL4540907 | 0.74 | ALDH1A1 (0.44) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL938483 | 0.67 | ALDH1A1 (0.38) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL42929 | 0.67 | ALDH1A1 (0.38) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL2505815 | 0.67 | ALDH1A1 (0.38) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL8517735 | 0.67 | ALDH1A1 (0.34) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL9495447 | 0.67 | TET2 (0.40) | MEN1ALDH1A1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981544-B1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF | KIST KOREA INSTITUTE OF SCIENCE AND TECH (KR) | 2019-06-19 | — | — | EP | disclosed |
| US-9526699-B2 | Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof | KIST (KR) | 2016-12-27 | — | — | US | disclosed |
| EP-1654302-B1 | THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME | KOREA INST SCI & TECH (KR) | 2014-09-17 | — | — | EP | disclosed |
| US-20090022683-A1 | Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof | KIST (KR) | 2009-01-22 | — | — | US | disclosed |
| EP-1981544-A2 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF | KIST Korea Institute of Science and Technology (KR) | 2008-10-22 | — | — | EP | disclosed |
| US-7259225-B2 | Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-08-21 | — | — | US | disclosed |
| WO-2007083875-A2 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-07-26 | — | — | WO | disclosed |
| EP-1654302-A1 | THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005010079-A1 | THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-02-03 | — | — | WO | disclosed |
| US-20050020808-A1 | Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-01-27 | — | — | US | disclosed |
| EP-1161480-B1 | BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD | KOREA INST SCI & TECH (KR) | 2004-12-22 | — | — | EP | disclosed |
| EP-1161480-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2001-12-12 | — | — | EP | disclosed |
| US-6319984-B1 | TEMPERATURE-SENSITIVITY AND BIODEGRADABILITY CAN BE CONTROLLED AS DESIRED BY SUBSTITUTING POLYDICHLOROPHOSPHAZENE WITH METHOXY HEPTA(ETHYLENE GLYCOL), DEPSIPEPTIDES AND AMINO ACID ESTERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2001-11-20 | — | — | US | disclosed |
| WO-2001036516-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022683-A1 | Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof | PHOSPHO1, PGLS, LIPE | MEN1 2005/4885ALDH1A1 3589/4885CYP1A2 3180/4885 |
| US-20050020808-A1 | Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same | PHOSPHO1, INPPL1, PLCG1 | MEN1 279/4885ALDH1A1 3295/4885CYP1A2 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.