Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764182 | 0.82 | — | — | |
| SCHEMBL23101 | 0.82 | — | — | |
| SCHEMBL3512818 | 0.82 | — | — | |
| SCHEMBL27756386 | 0.82 | — | — | |
| Vinylsulfonic Acid SCHEMBL4057155 | 0.80 | TSHR (0.33) | TSHR | |
| SCHEMBL28251068 | 0.79 | ALDH1A1 (0.38) | TSHR | |
| Sulfuric Acid SCHEMBL25265040 | 0.79 | CA5A (0.46) | TSHR | |
| Methyl Alcohol SCHEMBL9253309 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL18587180 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL1587516 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017726-B2 | Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-28 | — | — | US | claimed |
| US-8586020-B2 | Poly(organophosphazene) composition for biomaterials | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-11-19 | — | — | US | claimed |
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-01-03 | — | — | US | claimed |
| EP-2540764-A2 | Poly(organophosphazene) composition for biomaterials | Korea Institute of Science and Technology (KR) | 2013-01-02 | — | — | EP | claimed |
| US-8313771-B2 | Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-11-20 | — | — | US | claimed |
| US-20120202263-A1 | Bioactive Macromers and Hydrogels and Methods for Producing Same | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-08-09 | — | — | US | claimed |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | Korean Institute of Science and Technology of Seoul, Republic of Korea | 2012-05-17 | — | — | US | claimed |
| US-20100297155-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF | DECA ITALIA S.R.L. (IT) | 2010-11-25 | — | — | US | claimed |
| EP-2155806-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF | Korea Institute of Science and Technology (KR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008153278-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-12-18 | — | — | WO | claimed |
| EP-0906122-B1 | ACTIVATED LINKERS AND METHODS FOR MAKING AND PURIFYING THE SAME | AMGEN INC (US) | 2003-09-10 | — | — | EP | claimed |
| JP-2000506851-A | — | — | 2000-06-06 | — | — | JP | claimed |
| US-5935564-A | USING ABSORBER RESIN HAVING A BUTYL, OCTYL, PHENYL OR ETHER PENDANT GROUP TO PURIFY A POLYOXYETHYLENE GLYCOL HAVING SULFONYL CHLORIDE OR VINYLSULFONE END GROUPS FOR REACTING WITH AN INHIBITOR OF TUMOR NECROSIS FACTOR | AMGEN INC. (US) | 1999-08-10 | — | — | US | claimed |
| EP-0906122-A2 | ACTIVATED LINKERS AND METHODS FOR MAKING AND PURIFYING THE SAME | AMGEN INC. (US) | 1999-04-07 | — | — | EP | claimed |
| US-5747639-A | METHACRYLATE BACKBONE POLYMER AND BIS/VINYL SULFONE FOR CHROMATOGRAPHIC COLUMNS | AMGEN BOULDER INC. (US) | 1998-05-05 | — | — | US | claimed |
| WO-1997032607-A2 | ACTIVATED LINKERS AND METHODS FOR MAKING AND PURIFYING THE SAME | AMGEN INC. (US) | 1997-09-12 | — | — | WO | claimed |
| WO-2024030186-A1 | COMPOSITIONS AND METHODS RELATED TO MICROGELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-02-08 | — | — | WO | disclosed |
| EP-3866835-B1 | METHOD FOR MONITORING AUTOIMMUNE DISEASE | UNIV MICHIGAN REGENTS (US) | 2024-01-03 | — | — | EP | disclosed |
| WO-2006116156-A2 | TOXIN PEPTIDES WITH EXTENDED BLOOD HALFLIFE | AMGEN INC. (US) | 2006-11-02 | — | — | WO | disclosed |
| EP-0906122-B1 | ACTIVATED LINKERS AND METHODS FOR MAKING AND PURIFYING THE SAME | AMGEN INC (US) | 2003-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | PHOSPHO1, PGLS, PHYKPL | TSHR 4580/4885 |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | PHOSPHO1, HSPA2, FEM1B | TSHR 929/4885 |
| US-20100297155-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF | PRUNE1, PHYKPL, PAPSS1 | TSHR 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.