SCHEMBL2777161

SCHEMBL2777161

NS(=O)(=O)c1cc(C(F)(F)F)ccc1F

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 3/20 0.51
FEN1 P39748 3/20 0.51
KIF11 P52732 4/20 0.47
CA1 P00915 5/20 0.47
CA2 P00918 5/20 0.47
CA9 Q16790 4/20 0.47
CA12 O43570 2/20 0.47
PTGES2 Q9H7Z7 4/20 0.43
IDO1 P14902 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
SGK1 O00141 1/20 0.41
LMNA P02545 1/20 0.41
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30543023 1.00 ALOX5AP (0.51) ALOX5APFEN1KIF11CA1CA2
SCHEMBL16368631 0.85 CA1 (0.47) ALOX5APFEN1CA1CA2CA9
SCHEMBL19475016 0.81 HSD11B1 (0.39) ALOX5APFEN1CA1CA2CA9
SCHEMBL29927210 0.81 HSD11B1 (0.39) ALOX5APFEN1CA1CA2CA9
SCHEMBL2182720 0.81 KIF11 (0.47) ALOX5APFEN1KIF11CA1CA2
SCHEMBL12335461 0.81 ALOX5AP (0.50) ALOX5APFEN1KIF11
SCHEMBL29913652 0.81 CA1 (0.55) ALOX5APFEN1KIF11CA1CA2
SCHEMBL3204890 0.81 PDE2A (0.43) ALOX5APFEN1CA1CA2CA9
SCHEMBL18985068 0.81 CA1 (0.55) ALOX5APFEN1KIF11CA1CA2
SCHEMBL30161606 0.81 MEN1 (0.44) ALOX5APFEN1KIF11CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172264-B1 NOVEL POLYMERS CONTAINING GRAFTED BIS(SULFONYL)IMIDE SODIUM OR LITHIUM SALTS TO THE METHODS FOR THE PRODUCTION THEREOF, AND TO THE USES OF SAME AS ELECTROLYTES FOR BATTERIES CDP INNOVATION (FR) 2021-06-16 EP disclosed
CN-107001622-B Novel polymers containing grafted sodium or lithium bis (sulfonyl) imide salts, method for the production thereof and use thereof as battery electrolytes CDP创新公司 2020-01-07 CN disclosed
US-10141603-B2 Polymers containing grafted bis(sulfonyl)imide sodium or lithium salts, methods for production thereof and uses of same as electrolytes for batteries CPD INNOVATION (FR) 2018-11-27 US disclosed
CN-107001622-A New polymers, its preparation method and its purposes as cell electrolyte of double (sulfonyl) imines sodium or lithium salts containing grafting CDP创新公司 2017-08-01 CN disclosed
US-20170179526-A1 NOVEL POLYMERS CONTAINING GRAFTED BIS(SULFONYL)IMIDE SODIUM OR LITHIUM SALTS, METHODS FOR PRODUCTION THEREOF AND USES OF SAME AS ELECTROLYTES FOR BATTERIES CDP INNOVATION (FR) 2017-06-22 US disclosed
EP-3172264-A1 NOVEL POLYMERS CONTAINING GRAFTED BIS(SULFONYL)IMIDE SODIUM OR LITHIUM SALTS, TO THE METHODS FOR THE PRODUCTION THEREOF, AND TO THE USES OF SAME AS ELECTROLYTES FOR BATTERIES. CDP-Innovation (FR) 2017-05-31 EP disclosed
WO-2016012670-A1 NOVEL POLYMERS CONTAINING GRAFTED BIS(SULFONYL)IMIDE SODIUM OR LITHIUM SALTS, TO THE METHODS FOR THE PRODUCTION THEREOF, AND TO THE USES OF SAME AS ELECTROLYTES FOR BATTERIES. CDP INNOVATION (FR) 2016-01-28 WO disclosed
EP-2147915-B1 New cycloalkylated benzothiadiazine derivatives, method of preparing same and pharmaceutical compositions containing them SERVIER LAB (FR) 2010-09-15 EP disclosed
US-7741320-B2 Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2010-06-22 US disclosed
EP-2147915-A1 New cycloalkylated benzothiadiazine derivatives, method of preparing same and pharmaceutical compositions containing them Les Laboratoires Servier (FR) 2010-01-27 EP disclosed
US-20100009974-A1 Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compostions containing them LES LABORATOIRES SERVIER (FR) 2010-01-14 US disclosed
WO-2010004139-A1 NEW CYCLOALKYLATED BENZOTHIADIAZINE DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LES LABORATOIRES SERVIER (FR) 2010-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009974-A1 Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compostions containing them ACLY, HCAR1, GABRG1 ALOX5AP 725/4885FEN1 4663/4885KIF11 3841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.